概述

  • 产品名称Anti-CD1b+c抗体[B-B5] (FITC)
    参阅全部 CD1b+c 一抗
  • 描述
    小鼠单克隆抗体[B-B5] to CD1b+c (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性This antibody is specific for CD1b and c proteins.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Thymus cells and Jurkat cell line (Human)

性能

应用

Our Abpromise guarantee covers the use of ab27336 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 10µl for 106 cells or 100 µl of whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性CD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.
    • 细胞定位Single-pass type I membrane protein.
    • 数据库链接
    • 别名
      • CD1 antibody
      • CD1B antigen antibody
      • CD1b molecule antibody
      • CD1C antigen antibody
      • CD1c molecule antibody
      • R1 antibody
      • R7 antibody
      see all

    Anti-CD1b+c antibody [B-B5] (FITC) 图像

    • Staining pattern of Molt 4 cell line with ab27336 at 10ul/106 cells.

    Anti-CD1b+c antibody [B-B5] (FITC) (ab27336)参考文献

    This product has been referenced in:
    • Sancho D  et al. Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin. J Clin Invest 118:2098-2110 (2008). Flow Cyt ; Human . Read more (PubMed: 18497879) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"