Anti-CD19抗体[MB19-1] (PE/Cy5.5 ®) (ab25384)


  • 产品名称Anti-CD19抗体[MB19-1] (PE/Cy5.5 ®)
    参阅全部 CD19 一抗
  • 描述
    小鼠单克隆抗体[MB19-1] to CD19 (PE/Cy5.5 ®)
  • 偶联物PE/Cy5.5 ®. Ex: 496nm, Em: 690nm
  • 特异性CD19 B cell differentiation antigen, Mr 95 kDa.
  • 经测试应用适用于: Flow Cyt, IPmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    CD19+ mouse pre-B cell line, 300.19

  • 阳性对照
    • Mature B cells. All splenic and peritoneal IgM+ cells of B1 and B2 lineages.
  • 常规说明To ensure consistency of performance, each batch of monoclonal antibody is tested by flow cytometry to conform to characteristics of a standard reference reagent. This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.



Our Abpromise guarantee covers the use of ab25384 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use up to 0.2µg to label 106 cells.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
    • 疾病相关Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) [MIM:613493]; also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
    • 序列相似性Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    • 翻译后修饰Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Antibody deficiency due to defect in CD19, included antibody
      • AW495831 antibody
      • B lymphocyte antigen CD19 antibody
      • B lymphocyte surface antigen B4 antibody
      • B-lymphocyte antigen CD19 antibody
      • B-lymphocyte surface antigen B4 antibody
      • B4 antibody
      • CD19 antibody
      • CD19 antigen antibody
      • CD19 molecule antibody
      • Cd19 protein antibody
      • CD19_HUMAN antibody
      • CVID3 antibody
      • Differentiation antigen CD19 antibody
      • Leu 12 antibody
      • Leu-12 antibody
      • Leu12 antibody
      • MGC109570 antibody
      • MGC12802 antibody
      • T-cell surface antigen Leu-12 antibody
      see all

    Anti-CD19 antibody [MB19-1] (PE/Cy5.5 ®) (ab25384)参考文献

    ab25384 has not yet been referenced specifically in any publications.

    Product Wall

    Application Flow Cytometry
    Sample Dog Cell (Whole blood)
    Permeabilization No
    Gating Strategy Lymphocytes
    Specification Whole blood
    Preparation Cell harvesting/tissue preparation method: Whole blood washed in PBS and lysed
    Sample buffer: PBS

    Anushka George

    Verified customer

    提交于 Mar 15 2016

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