概述

  • 产品名称Anti-CD16+CD32抗体[93] (Biotin)
    参阅全部 CD16+CD32 一抗
  • 描述
    大鼠单克隆抗体[93] to CD16+CD32 (Biotin)
  • 偶联物Biotin
  • 特异性ab25249 recognises Murine CD16/32 (CD16/Fcgamma II and CD32/Fcgamma III receptors).
  • 经测试应用适用于: IP, Blocking, Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • 表位This antibody recognizes a conformational epitope formed by Fgamma II and Fcgamma III receptors.

性能

应用

Our Abpromise guarantee covers the use of ab25249 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent concentration.
Blocking Use at an assay dependent concentration.
Flow Cyt Use 3µg for 106 cells. ab18542-Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

靶标

  • 相关性Function: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. Tissue specificity: Found on monocytes, neutrophils and eosinophil platelets. Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. PTM: Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
  • 细胞定位CD32: Type I membrane protein. CD16: Attached to the membrane by a GPI anchor. Exists also as a soluble receptor, produced by a proteolytic cleavage.
  • 数据库链接
  • 别名
    • CD16a antibody
    • CD16b antibody
    • CD32 antibody
    • CD32A antibody
    • CD32B antibody
    • CDw32 antibody
    • Fc fragment of IgG low affinity IIa receptor antibody
    • Fc fragment of IgG low affinity IIb receptor antibody
    • Fc fragment of IgG low affinity IIIa receptor antibody
    • Fc fragment of IgG low affinity IIIb receptor antibody
    • Fc gamma receptor III A antibody
    • Fc gamma receptor IIIb antibody
    • Fc gamma RIIa antibody
    • Fc gamma RIIb antibody
    • Fc gamma RIII beta antibody
    • Fc-gamma RII-a antibody
    • Fc-gamma-RIIa antibody
    • FCG2A_HUMAN antibody
    • FcGR antibody
    • FCGR2A antibody
    • FCGR2B antibody
    • FCGR3 antibody
    • FCGR3A antibody
    • FCGR3B antibody
    • FcRII-a antibody
    • FcRIII antibody
    • IgG Fc receptor II-a antibody
    • Low affinity immunoglobulin gamma Fc region receptor II-a antibody
    see all

Anti-CD16+CD32 antibody [93] (Biotin) 图像

  • Flow cytomery analysis of BALB/c mouse splenocytes labeling CD16 + CD32 with ab25249 at 1 µg/106cells and CD19 with Rat Anti-Mouse CD19-PE followed by Streptavidin-FITC.

Anti-CD16+CD32 antibody [93] (Biotin) (ab25249)参考文献

This product has been referenced in:
  • Sankaran VG  et al. Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes Dev 26:2075-87 (2012). Read more (PubMed: 22929040) »

See 1 Publication for this product

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