概述

  • 产品名称Anti-CD16抗体[MEM-154]
    参阅全部 CD16 一抗
  • 描述
    小鼠单克隆抗体[MEM-154] to CD16
  • 特异性This antibody recognizes a polymorphism of human CD16a (NK cell form) and reacts well with the granulocyte form (CD16b) of all subjects. This antibody reacts with an epitope residing in proximity to FG loop (probably BC or C’E loop).
  • 经测试应用适用于: Flow Cyt, IP, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue/ cell preparation (Human granulocytes).

  • 阳性对照
    • blood lysate (leukocytes)

性能

应用

Our Abpromise guarantee covers the use of ab664 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB Use a concentration of 1 µg/ml. Use under non reducing condition.

靶标

  • 功能Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
  • 组织特异性Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
  • 序列相似性Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • 翻译后修饰Glycosylated. Contains high mannose- and complex-type oligosaccharides.
    The soluble form is produced by a proteolytic cleavage.
  • 细胞定位Cell membrane. Secreted. Exists also as a soluble receptor.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 16 antibody
    • CD 16a antibody
    • CD16 antibody
    • CD16a antibody
    • CD16a antigen antibody
    • CD16B antibody
    • CD16b antigen antibody
    • Fc fragment of IgG antibody
    • Fc fragment of IgG low affinity IIIa receptor (CD16) antibody
    • Fc fragment of IgG low affinity IIIa receptor antibody
    • Fc fragment of IgG receptor IIIa antibody
    • Fc fragment of IgG, low affinity III, receptor (CD16) antibody
    • Fc fragment of IgG, low affinity III, receptor for (CD16) antibody
    • Fc fragment of IgG, low affinity IIIa, receptor (CD16) antibody
    • Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody
    • Fc fragment of IgG, low affinity IIIa, receptor for antibody
    • Fc fragment of IgG, low affinity IIIb, receptor (CD16b) antibody
    • Fc fragment of IgG, low affinity IIIb, receptor for (CD16) antibody
    • Fc gamma R3 antibody
    • Fc gamma receptor III 2 (CD 16) antibody
    • Fc gamma receptor III A antibody
    • Fc gamma receptor IIIA antibody
    • Fc gamma receptor IIIb (CD 16) antibody
    • Fc gamma RIII alpha antibody
    • Fc gamma RIII antibody
    • Fc gamma RIII beta antibody
    • Fc gamma RIIIa antibody
    • Fc gamma RIIIb antibody
    • Fc of IgG antibody
    • Fc-gamma receptor III2 (CD 16) antibody
    • Fc-gamma receptor III2 (CD16) antibody
    • Fc-gamma receptor IIIb (CD16) antibody
    • Fc-gamma RIII antibody
    • Fc-gamma RIII-alpha antibody
    • Fc-gamma RIIIa antibody
    • FCG 3 antibody
    • FCG3 antibody
    • FCG3A_HUMAN antibody
    • FCgammaRIIIA antibody
    • FCGR 3 antibody
    • FCGR 3A antibody
    • FCGR3 antibody
    • FCGR3A antibody
    • FCGR3A protein antibody
    • FCGRIII antibody
    • FCGRIII-2 antibody
    • FcR 10 antibody
    • FcR-10 antibody
    • FcR10 antibody
    • FcRIII antibody
    • FcRIIIa antibody
    • IGFR 3 antibody
    • IGFR3 antibody
    • IgG Fc receptor III 1 antibody
    • IgG Fc receptor III 2 antibody
    • IgG Fc receptor III-2 antibody
    • IMD20 antibody
    • immunoglobulin G Fc receptor III antibody
    • immunoglobulin G Fc receptor III-2 antibody
    • Low affinity IIIa receptor antibody
    • Low affinity immunoglobulin gamma Fc region receptor III A antibody
    • Low affinity immunoglobulin gamma Fc region receptor III-A antibody
    • Low affinity immunoglobulin gamma Fc region receptor IIIB antibody
    • neutrophil-specific antigen NA antibody
    see all

Anti-CD16 antibody [MEM-154] 图像

  • Non-reducing conditions; dilution of antibody ab664 1 µg/ml
    Lane 1: leukocyte lysate
    Lane 2: JURKAT human cell line

Anti-CD16 antibody [MEM-154] (ab664)参考文献

This product has been referenced in:
  • Pinkaew D  et al. Morelloflavone, a biflavonoid inhibitor of migration-related kinases, ameliorates atherosclerosis in mice. Am J Physiol Heart Circ Physiol 302:H451-8 (2012). Read more (PubMed: 22058152) »
  • Kishimoto T. (Eds.) et al. Leucocyte typing VI. Garland Publishing Inc. : (1997). Read more (PubMed: ) »

See all 3 Publications for this product

Product Wall

Thank you for your enquiry. The antibody ab664 reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcγRIII antigen). This antibody recognizes a ...

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Thank you for submitting and enquiry. I am sorry to hear that you have been experiencing problems with ab664 in western blot. Often it is possible to make suggestions that help resolve problems. We will happily offer technical support and in the ev...

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Thank you for your enquiry. I have contacted the originator of this antibody and ab664 has not been tested by them for application in blocking. I updated the online datasheet to reflect this information and apologize for this. They also mentioned that ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"