PE Anti-CD16抗体[3G8] (ab117117)
Key features and details
- PE Mouse monoclonal [3G8] to CD16
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
概述
-
产品名称
PE Anti-CD16抗体[3G8]
参阅全部 CD16 一抗 -
描述
PE小鼠单克隆抗体[3G8] to CD16 -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD16. Human neutrophils.
-
阳性对照
- Flow Cyt: Lymphocytes from human blood.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 99% PBS, 0.2% BSA -
Concentration information loading...
-
纯度
Size exclusion -
克隆
单克隆 -
克隆编号
3G8 -
同种型
IgG1 -
研究领域
相关产品
-
Alternative Versions
- PerCP Anti-CD16 antibody [3G8] (ab130761)
- PerCP/Cy5.5® Anti-CD16 antibody [3G8], prediluted (ab157322)
- Anti-CD16 antibody [3G8] - Low endotoxin, Azide free (ab176528)
- Alexa Fluor® 488 Anti-CD16 antibody [3G8] (ab187585)
- APC/Cy7® Anti-CD16 antibody [3G8], prediluted (ab197141)
- PE/Cy7® Anti-CD16 antibody [3G8] (ab234209)
- FITC Anti-CD16 antibody [3G8] (ab239254)
- Alexa Fluor® 647 Anti-CD16 antibody [3G8] (ab239275)
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab117117于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
说明 |
---|
Flow Cyt
Use at an assay dependent concentration. 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
靶标
-
功能
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. -
组织特异性
Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts. -
序列相似性
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
翻译后修饰
Glycosylated. Contains high mannose- and complex-type oligosaccharides.
The soluble form is produced by a proteolytic cleavage. -
细胞定位
Cell membrane. Secreted. Exists also as a soluble receptor. - Information by UniProt
-
数据库链接
- Entrez Gene: 2214 Human
- Omim: 146740 Human
- SwissProt: P08637 Human
- Unigene: 372679 Human
-
别名
- CD 16 antibody
- CD 16a antibody
- CD16 antibody
see all
图片
-
Flow cytometry multicolor surface staining pattern of human lymphocytes using ab117117 at (20 µL reagent/100 µL of peripheral whole blood) and anti-human CD3 APC antibody at (10 µL reagent/100 µL of peripheral whole blood).
-
Flow cytometry surface staining pattern of human peripheral whole blood stained using ab117117 at (20 µL reagent/100 µL of peripheral whole blood).
-
Separation of human CD3 negative CD16 positive NK cells (red-filled) from human CD3 positive CD16 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using ab117117 at (20 µL reagent/100 µL of peripheral whole blood).
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab117117 被引用在 1 文献中.
- Congy-Jolivet N et al. Fc gamma RIIIa expression is not increased on natural killer cells expressing the Fc gamma RIIIa-158V allotype. Cancer Res 68:976-80 (2008). PubMed: 18281470