Anti-CD146抗体[c264] (Phycoerythrin) (ab25435)


  • 产品名称Anti-CD146抗体[c264] (Phycoerythrin)
    参阅全部 CD146 一抗
  • 描述
    小鼠单克隆抗体[c264] to CD146 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性ab25435 recognise Chicken MCAM, Mr 98 kDa (protein core ˜84 kDa).
  • 经测试应用适用于: Flow Cyt, IP, IHC-Frmore details
  • 种属反应性
    与反应: Chicken
  • 免疫原

    Pooled Ed15 and Ed16 thymocytes from H.B15, H.B19 and H.B21 chicken embryos



Our Abpromise guarantee covers the use of ab25435 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.2µg for 106 cells.
IP Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.


  • 功能Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
  • 组织特异性Detected in endothelial cells in vascular tissue throughout the body. May appear at the surface of neural crest cells during their embryonic migration. Appears to be limited to vascular smooth muscle in normal adult tissues. Associated with tumor progression and the development of metastasis in human malignant melanoma. Expressed most strongly on metastatic lesions and advanced primary tumors and is only rarely detected in benign melanocytic nevi and thin primary melanomas with a low probability of metastasis.
  • 序列相似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 别名
    • A32 antigen antibody
    • CD 146 antibody
    • CD146 antibody
    • CD146 antigen antibody
    • Cell surface glycoprotein MUC18 antibody
    • Cell surface glycoprotein P1H12 antibody
    • Gicerin antibody
    • Mcam antibody
    • Melanoma adhesion molecule antibody
    • Melanoma associated antigen A32 antibody
    • Melanoma associated antigen MUC18 antibody
    • Melanoma associated glycoprotein MUC18 antibody
    • Melanoma cell adhesion molecule antibody
    • Melanoma-associated antigen A32 antibody
    • Melanoma-associated antigen MUC18 antibody
    • MelCAM antibody
    • MUC 18 antibody
    • MUC18 antibody
    • MUC18_HUMAN antibody
    • S endo 1 antibody
    • S endo 1 endothelial associated antigen antibody
    • S-endo 1 endothelial-associated antigen antibody
    see all

Anti-CD146 antibody [c264] (Phycoerythrin) 图像

  • Flow cytometry analysis staining CD146 in chicken thymocytes using ab25435 at a dilution of 0.1 ug/106 cells. Mouse anti-chicken MCAM-PE was used as an isotype control.

Anti-CD146 antibody [c264] (Phycoerythrin) (ab25435)参考文献

ab25435 has not yet been referenced specifically in any publications.

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