Anti-CD14抗体[UCHM-1] (ab78333)

概述

  • 产品名称Anti-CD14抗体[UCHM-1]
    参阅全部 CD14 一抗
  • 描述
    小鼠单克隆抗体[UCHM-1] to CD14
  • 经测试应用适用于: IHC-Fr, ICC/IF, IP, Flow Cytmore details
  • 种属反应性
    与反应: Human, Monkey, Rhesus monkey
  • 免疫原

    Human thymocytes and peripheral blood mononuclear cells from an AML patient

性能

应用

Our Abpromise guarantee covers the use of ab78333 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
  • 组织特异性Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
  • 序列相似性Contains 11 LRR (leucine-rich) repeats.
  • 翻译后修饰N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 14 antibody
    • CD_antigen=CD14 antibody
    • CD14 antibody
    • CD14 antigen antibody
    • CD14 molecule antibody
    • CD14_HUMAN antibody
    • LPS-R antibody
    • Mo2 antibody
    • Monocyte differentiation antigen CD14 antibody
    • Monocyte differentiation antigen CD14 urinary form antibody
    • Monocyte differentiation antigen CD14, membrane-bound form antibody
    • Myeloid cell specific leucine rich glycoprotein antibody
    • Myeloid cell-specific leucine-rich glycoprotein antibody
    see all

Anti-CD14 antibody [UCHM-1] (ab78333)参考文献

ab78333 has not yet been referenced specifically in any publications.

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