Anti-CD14抗体[Tuk4] (Phycoerythrin) (ab23767)

概述

  • 产品名称
    Anti-CD14抗体[Tuk4] (Phycoerythrin)
    参阅全部 CD14 一抗
  • 描述
    小鼠单克隆抗体[Tuk4] to CD14 (Phycoerythrin)
  • 偶联物
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性
    ab23767 recognises CD14.
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    The details of the immunogen for this antibody are not available.

性能

应用

Our Abpromise guarantee covers the use of ab23767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 5µl for 106 cells.

靶标

  • 功能
    Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
  • 组织特异性
    Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
  • 序列相似性
    Contains 11 LRR (leucine-rich) repeats.
  • 翻译后修饰
    N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 14 antibody
    • CD_antigen=CD14 antibody
    • CD14 antibody
    • CD14 antigen antibody
    • CD14 molecule antibody
    • CD14_HUMAN antibody
    • LPS-R antibody
    • Mo2 antibody
    • Monocyte differentiation antigen CD14 antibody
    • Monocyte differentiation antigen CD14 urinary form antibody
    • Monocyte differentiation antigen CD14, membrane-bound form antibody
    • Myeloid cell specific leucine rich glycoprotein antibody
    • Myeloid cell-specific leucine-rich glycoprotein antibody
    see all

文献

This product has been referenced in:
  • Qeska V  et al. Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription. PLoS One 9:e96121 (2014). Flow Cyt . Read more (PubMed: 24769532) »
  • Slobedman B  et al. Latent cytomegalovirus down-regulates major histocompatibility complex class II expression on myeloid progenitors. Blood 100:2867-73 (2002). Read more (PubMed: 12351397) »

See all 2 Publications for this product

客户评价及客户问答

The concentration for thihas not been determined.

We have just determined the dilution factor useful for this antibody in flow cytometry, which is approximately 5 μl is required per 1,000,000 cells.
Sorry I could not be more helpful i...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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