Anti-CD14抗体[MEM-18] (Biotin) (ab21889)

概述

  • 产品名称
    Anti-CD14抗体[MEM-18] (Biotin)
    参阅全部 CD14 一抗
  • 描述
    小鼠单克隆抗体[MEM-18] to CD14 (Biotin)
  • 偶联物
    Biotin
  • 经测试应用
    适用于: Flow Cyt, IP, WB, ELISA, Functional Studiesmore details
  • 种属反应性
    与反应: Human
    预测可用于: Non human primates
  • 免疫原

    A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.

  • 常规说明

    Purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

性能

应用

Our Abpromise guarantee covers the use of ab21889 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/1 - 1/1000. ab18434-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 40 kDa.
ELISA Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.

靶标

  • 功能
    Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
  • 组织特异性
    Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
  • 序列相似性
    Contains 11 LRR (leucine-rich) repeats.
  • 翻译后修饰
    N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 14 antibody
    • CD_antigen=CD14 antibody
    • CD14 antibody
    • CD14 antigen antibody
    • CD14 molecule antibody
    • CD14_HUMAN antibody
    • LPS-R antibody
    • Mo2 antibody
    • Monocyte differentiation antigen CD14 antibody
    • Monocyte differentiation antigen CD14 urinary form antibody
    • Monocyte differentiation antigen CD14, membrane-bound form antibody
    • Myeloid cell specific leucine rich glycoprotein antibody
    • Myeloid cell-specific leucine-rich glycoprotein antibody
    see all

文献

ab21889 has not yet been referenced specifically in any publications.

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