Anti-CD11+CD18抗体[YKIX 490.6.4] (ab23397)

概述

  • 产品名称Anti-CD11+CD18抗体[YKIX 490.6.4]
    参阅全部 CD11+CD18 一抗
  • 描述
    大鼠单克隆抗体[YKIX 490.6.4] to CD11+CD18
  • 经测试应用适用于: Flow Cyt, IPmore details
    不适用于: IHC-Fr,IHC-P or IHC-R
  • 种属反应性
    与反应: Dog
  • 免疫原

    Tissue/ cell preparation (Dog). Canine thymocytes.

  • 常规说明


    This antibody has been assigned to the canine CD11/18 group, recognising a cell surface antigen of 90/180kD which is expressed by most leucocytes, although expression on peripheral blood lymphocytes is weak. This antibody blocks T cell proliferation, CTL and ADCC killing, and homotypic adhesion.

性能

应用

Our Abpromise guarantee covers the use of ab23397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/50 - 1/100.

Use 10µl of working dilution for 106 cells in 100 µl.





ab18703-Rat monoclonal IgG2c, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
  • 应用说明Is unsuitable for IHC-Fr,IHC-P or IHC-R.
  • 靶标

    • 功能Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
    • 组织特异性Leukocytes.
    • 序列相似性Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • 结构域The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • 细胞定位Membrane.
    • Information by UniProt
    • 别名
      • Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
      • CD11 antigen-like family member A antibody
      • CD11a antibody
      • CD18 antibody
      • CR3 antibody
      • Integrin alpha-L antibody
      • Integrin beta 2 antibody
      • Integrin gene promoter antibody
      • ITAL_HUMAN antibody
      • Itgal antibody
      • ITGAM antibody
      • ITGB2 antibody
      • LAD antibody
      • Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
      • Leukocyte function-associated molecule 1 alpha chain antibody
      • LFA 1 alpha antibody
      • LFA 1 antibody
      • LFA-1A antibody
      • LFA1 antibody
      • LFA1A antibody
      • Lymphocyte function associated antigen 1 antibody
      • MAC1 antibody
      • MFI7 antibody
      • MO1A antibody
      see all

    Anti-CD11+CD18 antibody [YKIX 490.6.4] (ab23397)参考文献

    ab23397 has not yet been referenced specifically in any publications.

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