PerCP荧光/Cy5.5® Anti-CD11c抗体[N418] (ab111469)
Key features and details
- PerCP/Cy5.5® Armenian hamster monoclonal [N418] to CD11c
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PerCP/Cy5.5®. Ex: 482nm, Em: 690nm
- Isotype: IgG
Related conjugates and formulations
概述
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产品名称
PerCP荧光/Cy5.5® Anti-CD11c抗体[N418]
参阅全部 CD11c 一抗 -
描述
PerCP荧光/Cy5.5®亚美尼亚仓鼠单克隆抗体[N418] to CD11c -
宿主
Armenian hamster -
偶联物
PerCP/Cy5.5®. Ex: 482nm, Em: 690nm -
特异性
N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse CD11c. Mouse spleen dendritic cells
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阳性对照
- Splenocytes.
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常规说明
Excitation wavelength: 488 nm. Emission wavelength: 690 nm.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.16% Sodium phosphate, 0.1% Gelatin -
Concentration information loading...
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纯度
Affinity purified -
克隆
单克隆 -
克隆编号
N418 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
- Anti-CD11c antibody [N418] - Low endotoxin, Azide free (ab185783)
- APC Anti-CD11c antibody [N418] (ab210306)
- APC/Cy7® Anti-CD11c antibody [N418] (ab210307)
- FITC Anti-CD11c antibody [N418] (ab210308)
- PE Anti-CD11c antibody [N418] (ab210309)
- PE/Cy7® Anti-CD11c antibody [N418] (ab210310)
- Alexa Fluor® 647 Anti-CD11c antibody [N418] (ab233046)
- Anti-CD11c antibody [N418] - BSA and Azide free (ab233173)
- violetFluor™ 450 Anti-CD11c antibody [N418] (ab242269)
- Anti-CD11c antibody [N418] (ab33483)
- Alexa Fluor® 488 Anti-CD11c antibody [N418] (ab33503)
- Biotin Anti-CD11c antibody [N418] (ab95765)
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111469于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Flow Cyt |
Use at an assay dependent concentration.
This can be used at less than or equal to 0.25µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number shouldbe determined empirically but can range from 10^5 to 10^8 cells/test. |
说明 |
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Flow Cyt
Use at an assay dependent concentration. This can be used at less than or equal to 0.25µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number shouldbe determined empirically but can range from 10^5 to 10^8 cells/test. |
靶标
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功能
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. -
组织特异性
Predominantly expressed in monocytes and granulocytes. -
序列相似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
结构域
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 16411 Mouse
- SwissProt: Q9QXH4 Mouse
- Unigene: 22378 Mouse
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别名
- 95 alpha chain antibody
- 95 antibody
- CD 11c antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab111469 被引用在 1 文献中.
- Chen Y et al. Prevotellaceae produces butyrate to alleviate PD-1/PD-L1 inhibitor-related cardiotoxicity via PPARα-CYP4X1 axis in colonic macrophages. J Exp Clin Cancer Res 41:1 (2022). PubMed: 34980222