Anti-CD11c抗体[FK24] (ab23602)
Key features and details
- Mouse monoclonal [FK24] to CD11c
- Suitable for: ICC, ICC/IF
- Reacts with: Human
- Isotype: IgG1
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-CD11c抗体[FK24]
参阅全部 CD11c 一抗 -
描述
小鼠单克隆抗体[FK24] to CD11c -
宿主
Mouse -
经测试应用
适用于: ICC, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD11c.
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常规说明
ab23602 can be used for the identification of CD11c-positive cells using immunoperoxidase procedures. It can thus be used for the identification of monocytes and granylocytes using immunoperoxidase procedures. In addition it seems useful for identification of myelomonocytic and monocytic leukemias.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.3
Constituent: Ascites -
Concentration information loading...
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纯度
Protein A purified -
Primary antibody说明
ab23602 can be used for the identification of CD11c-positive cells using immunofluorescence or immunoperoxidase procedures. It can thus be used for the identification of monocytes and granylocytes using either immunofluorescence or immunoperoxidase procedures. In addition it seems useful for identification of myelomonocytic and monocytic leukemias. -
克隆
单克隆 -
克隆编号
FK24 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab23602于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC |
Use at an assay dependent concentration.
Dilute antibody preferably in PBS plus 1% BSA and 0.01% Na-azide. |
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ICC/IF | (1) |
Use at an assay dependent concentration.
Dilute antibody preferably in PBS plus 1% BSA and 0.01% Na-azide. |
说明 |
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ICC
Use at an assay dependent concentration. Dilute antibody preferably in PBS plus 1% BSA and 0.01% Na-azide. |
ICC/IF
Use at an assay dependent concentration. Dilute antibody preferably in PBS plus 1% BSA and 0.01% Na-azide. |
靶标
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功能
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. -
组织特异性
Predominantly expressed in monocytes and granulocytes. -
序列相似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
结构域
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 3687 Human
- Omim: 151510 Human
- SwissProt: P20702 Human
- Unigene: 248472 Human
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别名
- 95 alpha chain antibody
- 95 antibody
- CD 11c antibody
see all
数据表及文件
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Datasheet download
文献 (1)
ab23602 被引用在 1 文献中.
- Rane JK et al. Conserved two-step regulatory mechanism of human epithelial differentiation. Stem Cell Reports 2:180-8 (2014). ICC/IF ; Human . PubMed: 24527392