Anti-CD11b/c抗体[OX42] (FITC) (ab112170)


  • 产品名称
    Anti-CD11b/c抗体[OX42] (FITC)
    参阅全部 CD11b/c 一抗
  • 描述
    小鼠单克隆抗体[OX42] to CD11b/c (FITC)
  • 偶联物
    FITC. Ex: 493nm, Em: 528nm
  • 经测试应用
    适用于: Flow Cytmore details
    不适用于: IHC-Fr
  • 种属反应性
    与反应: Rat
  • 免疫原

    Rat Peritoneal Macrophages.

  • 阳性对照
    • Fisher Rat Peritoneal Macrophages.
  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.



Our Abpromise guarantee covers the use of ab112170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.01-0.1µg for 106 cells. ab91362-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
  • 应用说明
    Is unsuitable for IHC-Fr.
  • 靶标

    • 功能
      Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
    • 组织特异性
      Predominantly expressed in monocytes and granulocytes.
    • 疾病相关
      Systemic lupus erythematosus 6
    • 序列相似性
      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • 结构域
      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • 细胞定位
    • Information by UniProt
    • 数据库链接
    • 别名
      • Antigen CD11b (p170) antibody
      • CD11 antigen like family member B antibody
      • CD11 antigen like family member C antibody
      • CD11 antigen-like family member B antibody
      • CD11b antibody
      • CD11C antibody
      • Cell surface glycoprotein MAC 1 subunit alpha antibody
      • Cell surface glycoprotein MAC-1 subunit alpha antibody
      • CR 3 alpha chain antibody
      • CR-3 alpha chain antibody
      • CR3A antibody
      • Integrin alpha M antibody
      • Integrin alpha X antibody
      • Integrin alpha-M antibody
      • Integrin, alpha M (complement component 3 receptor 3 subunit) antibody
      • Integrin, alpha X (antigen CD11C (p150), alpha polypeptide) antibody
      • Integrin, alpha X (complement component 3 receptor 4 subunit) antibody
      • ITAM_HUMAN antibody
      • ITGAM antibody
      • ITGAX antibody
      • Leu M5, alpha subunit antibody
      • Leukocyte adhesion glycoprotein p150,95 alpha chain antibody
      • Leukocyte adhesion receptor MO1 antibody
      • Leukocyte adhesion receptor p150,95 antibody
      • Leukocyte surface antigen p150,95, alpha subunit antibody
      • MAC 1 antibody
      • MAC1A antibody
      • Macrophage antigen alpha polypeptide antibody
      • MGC117044 antibody
      • MO1A antibody
      • Myeloid membrane antigen, alpha subunit antibody
      • Neutrophil adherence receptor alpha M subunit antibody
      • Neutrophil adherence receptor antibody
      • OTTHUMP00000163299 antibody
      • p150 95 integrin alpha chain antibody
      • SLEB6 antibody
      see all

    Anti-CD11b/c antibody [OX42] (FITC) 图像

    • ab112170 at 0.06 µg/106 cells staining CD11b/c in Rat Peritoneal Macrophages (Fisher strain) by Flow Cytometry.
      Percentage of cells stained above control (FITC Mouse IgG2a, k): 99%.

    Anti-CD11b/c antibody [OX42] (FITC) (ab112170)参考文献

    ab112170 has not yet been referenced specifically in any publications.

    Product Wall

    Immunohistochemistry (Frozen sections)
    Rat Tissue sections (Brain)
    Blocking step
    Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10%

    Abcam user community

    Verified customer

    提交于 Oct 03 2012

    Thank you for your enquiry and your interest in our products.

    I can confirm that this antibody (ab52478: Anti-CD11b antibody [EP1345Y]) is raised in rabbit; it has been tested for cross-reactivity only with mouse and human CD11b. It has not b...

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