Anti-CD105抗体[MJ7/18] (Phycoerythrin) (ab93567)

概述

  • 产品名称Anti-CD105抗体[MJ7/18] (Phycoerythrin)
    参阅全部 CD105 一抗
  • 描述
    大鼠单克隆抗体[MJ7/18] to CD105 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Tissue/ cell preparation: inflamed Mouse skin.

  • 阳性对照
    • Mouse brain derived endothelial (bEnd.3) cells and splenocytes

性能

应用

Our Abpromise guarantee covers the use of ab93567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.25-0.5µg for 105-8 cells. ab134674-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • 组织特异性Endoglin is restricted to endothelial cells in all tissues except bone marrow.
  • 疾病相关Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI528660 antibody
    • AI662476 antibody
    • CD 105 antibody
    • CD105 antibody
    • CD105 antigen antibody
    • EGLN_HUMAN antibody
    • END antibody
    • Endoglin antibody
    • Eng antibody
    • FLJ41744 antibody
    • HHT1 antibody
    • ORW antibody
    • ORW1 antibody
    • Osler Rendu Weber syndrome 1 antibody
    • RP11 228B15.2 antibody
    • S-endoglin antibody
    • SN6 antibody
    see all

Anti-CD105 antibody [MJ7/18] (Phycoerythrin) 图像

  • Staining of bEnd.3 cells with 0.25 µg of PE Rat IgG2a Isotype Control (open histogram) or 0.25 µg of ab93567 (colored histogram). Total viable cells were used for analysis.

Anti-CD105 antibody [MJ7/18] (Phycoerythrin) (ab93567)参考文献

This product has been referenced in:
  • Yamamoto M  et al. Osteogenic Potential of Mouse Adipose-Derived Stem Cells Sorted for CD90 and CD105 In Vitro. Stem Cells Int 2014:576358 (2014). Flow Cyt ; Mouse . Read more (PubMed: 25302065) »
  • Pérez-Gómez E  et al. A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis. Cancer Res 67:10268-77 (2007). WB . Read more (PubMed: 17974968) »

See all 5 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"