Anti-CD105抗体[MEM-229] (Phycoerythrin) (ab53321)

概述

  • 产品名称
    Anti-CD105抗体[MEM-229] (Phycoerythrin)
    参阅全部 CD105 一抗
  • 描述
    小鼠单克隆抗体[MEM-229] to CD105 (Phycoerythrin)
  • 偶联物
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用
    适用于: WB, IHC-Fr, ICC, Flow Cytmore details
  • 种属反应性
    与反应: Human, Pig
  • 免疫原

    Recombinant vaccinia virus containing human CD105 (L-isoform) cDNA

性能

应用

Our Abpromise guarantee covers the use of ab53321 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Use under non reducing condition. Predicted molecular weight: 71 kDa.
IHC-Fr 1/200. Fix with acetone.
ICC Use at an assay dependent concentration.
Flow Cyt Use 20µl for 106 cells. (or 100µl of whole blood).



ab91363-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能
    Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • 组织特异性
    Endoglin is restricted to endothelial cells in all tissues except bone marrow.
  • 疾病相关
    Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI528660 antibody
    • AI662476 antibody
    • CD 105 antibody
    • CD105 antibody
    • CD105 antigen antibody
    • EGLN_HUMAN antibody
    • END antibody
    • Endoglin antibody
    • Eng antibody
    • FLJ41744 antibody
    • HHT1 antibody
    • ORW antibody
    • ORW1 antibody
    • Osler Rendu Weber syndrome 1 antibody
    • RP11 228B15.2 antibody
    • S-endoglin antibody
    • SN6 antibody
    see all

Anti-CD105 antibody [MEM-229] (Phycoerythrin) 图像

  • ab53318 staining CD105 in infarcted porcine heart by Immunohistochemistry (Frozen sections). Cell nuclei were counterstained blue with DAPI.

Anti-CD105 antibody [MEM-229] (Phycoerythrin) (ab53321)参考文献

This product has been referenced in:
  • Borghesi J  et al. Phenotype and multipotency of rabbit (Oryctolagus cuniculus) amniotic stem cells. Stem Cell Res Ther 8:27 (2017). Read more (PubMed: 28173846) »
  • Zhao F  et al. Programmed cell death 1 correlates with the occurrence and development of MG63 osteosarcoma. Oncol Lett 12:5199-5204 (2016). Flow Cyt ; Human . Read more (PubMed: 28105229) »

See all 5 Publications for this product

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Attached please find the list of our antibodies that have been validated for use in Flow Cytometry on sheep cells.

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The IgG concentration of lot GR37350 is 60ug/ml.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Thank you for your enquiry. I am afraid that according to the supplier of the product, the exact concentration for this product is proprietary and can not be released. The only information they will provide is the number of tests and dilution facto...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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