概述

  • 产品名称
    Anti-CD105抗体[MEM-226] (FITC)
    参阅全部 CD105 一抗
  • 描述
    小鼠单克隆抗体[MEM-226] to CD105 (FITC)
  • 偶联物
    FITC. Ex: 493nm, Em: 528nm
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant Vaccinia virus containing the human CD105 cDNA.

  • 常规说明

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.

性能

应用

Our Abpromise guarantee covers the use of ab18278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. 20 µl for 100 µl sample is recommended.



ab91362-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能
    Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • 组织特异性
    Endoglin is restricted to endothelial cells in all tissues except bone marrow.
  • 疾病相关
    Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI528660 antibody
    • AI662476 antibody
    • CD 105 antibody
    • CD105 antibody
    • CD105 antigen antibody
    • EGLN_HUMAN antibody
    • END antibody
    • Endoglin antibody
    • Eng antibody
    • FLJ41744 antibody
    • HHT1 antibody
    • ORW antibody
    • ORW1 antibody
    • Osler Rendu Weber syndrome 1 antibody
    • RP11 228B15.2 antibody
    • S-endoglin antibody
    • SN6 antibody
    see all

图片

  • Flow cytometry analysis of rat bone marrow mesenchymal stem cells, staining CD105 (blue histograms) with ab18278.

    Cells were cultured in were isolated from young (YBM-MSC) and old (OBM-MSC) Sprague Dawley rats. The sample was incubated with the primary antibody (1/100) for 30 minutes on ice.

文献

This product has been referenced in:
  • Hong L  et al. The effects of 17-ß estradiol on enhancing proliferation of human bone marrow mesenchymal stromal cells in vitro. Stem Cells Dev 20:925-31 (2011). Flow Cyt ; Human . Read more (PubMed: 20735179) »
  • Asumda FZ & Chase PB Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. BMC Cell Biol 12:44 (2011). Flow Cyt ; Rat . Read more (PubMed: 21992089) »

See all 4 Publications for this product

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