Anti-CD105抗体[105C02] (ab44967)


  • 产品名称Anti-CD105抗体[105C02]
    参阅全部 CD105 一抗
  • 描述
    小鼠单克隆抗体[105C02] to CD105
  • 经测试应用适用于: IHC-Fr, IHC-P, WB, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Purified GP160 from cell membrane glycoproteins of fresh non-T/non-B acute lymphoblastic leukemia cells.

  • 阳性对照
    • HUVEC cells.



Our Abpromise guarantee covers the use of ab44967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration. PubMed: 24714106
IHC-P 1/1000. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
WB 1/1000. Detects a band of approximately 95 kDa.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • 功能Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • 组织特异性Endoglin is restricted to endothelial cells in all tissues except bone marrow.
  • 疾病相关Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI528660 antibody
    • AI662476 antibody
    • CD 105 antibody
    • CD105 antibody
    • CD105 antigen antibody
    • EGLN_HUMAN antibody
    • END antibody
    • Endoglin antibody
    • Eng antibody
    • FLJ41744 antibody
    • HHT1 antibody
    • ORW antibody
    • ORW1 antibody
    • Osler Rendu Weber syndrome 1 antibody
    • RP11 228B15.2 antibody
    • S-endoglin antibody
    • SN6 antibody
    see all

Anti-CD105 antibody [105C02] (ab44967)参考文献

This product has been referenced in:
  • Dziasko MA  et al. Localisation of epithelial cells capable of holoclone formation in vitro and direct interaction with stromal cells in the native human limbal crypt. PLoS One 9:e94283 (2014). IHC-Fr ; Human . Read more (PubMed: 24714106) »

See 1 Publication for this product

Product Wall

I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement for one vial of ab49679.

To check the status of the order please contact o...

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Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Rabbit Tissue sections (Insitional back wound)
Antigen retrieval step Enzymatic
Permeabilization No
Specification Insitional back wound
Blocking step Dako Dual Endogenous Enzyme Block as blocking agent for 5 minute(s) · Concentration: 100% · Temperature: 37°C
Fixative Formaldehyde

Abcam user community

Verified customer

提交于 Jun 29 2016

Application Immunocytochemistry/ Immunofluorescence
Blocking step BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 25°C
Sample Human Cell (Human primary mesenchymal stem cells grown in 3-D)
Specification Human primary mesenchymal stem cells grown in 3-D
Permeabilization No
Fixative Formaldehyde

Abcam user community

Verified customer

提交于 Feb 16 2015

Thank you for contacting Abcam.
Earlier today we discussed the Human Mesenchymal Stromal Cell Marker panel ab93758. Based on the information on the datasheet, I compiled the following information for you:
1. Positive selection (CD105, CD29, CD4...

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Hello! I have pasted the protocols below. Please let me know if you have any further questions!
Proteinase K Solution (Method 1) (20 ug/ml in TE Buffer, pH 8.0):

TE Buffer (50mM Tris Base, 1mM EDTA, 0.5% Triton X-100, pH 8.0):
Tris Bas...

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Thank you for contacting us. I have placed information abou the trypsin solution and enzymatic antigen retrieval below.
I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information. Read More

Thank you for contacting us.

I am sorry to hear you are experiencing difficulties with one of our products. We take product complaints very seriously, and investigate every product that we feel may not be performing correctly.

I am at...

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Thank you very much for your calls today and for letting us know about the trouble with ab44967 and these other CD105 antibodies.

As we discussed, I'm sending a free of charge vial of ab11414 on the order ***, which should arrive tomorrow. Pl...

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Thank you for your enquiry and interest in our products.

I can confirm that this panel contains 5 primary antibodies which recognize human mesenchymal stromal cells: ab6124, ab10559, ab23894, ab44967, ab52971. The datasheets can be found at t...

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Just wanted you to know I have found your order on our system. I will follow up with you shortly when have set up the replacement order.