The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明Flow Cyt: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
Does not inhibit the Mixed Lymphocyte Culture.
Cytotoxic in association with the Rabbit Complement on CD10+ Cells.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Naderi EH et al. Selective inhibition of cell death in malignant vs normal B-cell precursors: implications for cAMP in development and treatment of BCP-ALL. Blood121:1805-13 (2013).
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