概述

  • 产品名称Anti-CCRK抗体
    参阅全部 CCRK 一抗
  • 描述
    兔多克隆抗体to CCRK
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 159-208 (FGLARVFSPD GSRLYTHQVA TRSVGCIMGE LLNGSPLFPG KNDIEQLCYV) of Human CCRK (NP_848519).

  • 阳性对照
    • RPMI-8226 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab122996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
  • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • 细胞定位Nucleus. Cytoplasm. Cell projection > cilium.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CAK kinase p42 antibody
    • CAK-kinase p42 antibody
    • CCRK antibody
    • CDCH antibody
    • CDK activating kinase p42 antibody
    • CDK-activating kinase p42 antibody
    • cdk20 antibody
    • CDK20_HUMAN antibody
    • Cell cycle related kinase antibody
    • Cell cycle-related kinase antibody
    • Cell division protein kinase 20 antibody
    • Cyclin dependent protein kinase H antibody
    • Cyclin kinase activating kinase p42 antibody
    • Cyclin-dependent kinase 20 antibody
    • Cyclin-dependent protein kinase H antibody
    • Cyclin-kinase-activating kinase p42 antibody
    • p42 antibody
    • PNQALRE antibody
    see all

Anti-CCRK antibody 图像

  • Anti-CCRK antibody (ab122996) at 1 µg/ml + RPMI-8226 cell lysate at 10 µg

    Predicted band size : 39 kDa

Anti-CCRK antibody (ab122996)参考文献

ab122996 has not yet been referenced specifically in any publications.

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