概述

  • 产品名称Anti-CCR9抗体[E99]
    参阅全部 CCR9 一抗
  • 描述
    兔单克隆抗体[E99] to CCR9
  • 特异性The antibody is specific to CCR9. It does not cross react with other G protein coupled receptor 1 family members.
  • 经测试应用适用于: WB, ICC, Flow Cytmore details
    不适用于: IHC or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CCR9 (N terminal). The exact sequence is proprietary. A synthetic peptide corresponding to an extracellular domain of human CCR9.

  • 阳性对照
    • K562 and Daudi cell lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Alternative versions available:

    Anti-CCR9 antibody (HRP) [E99] (ab201829)

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • Concentration information loading...
  • 克隆单克隆
  • 克隆编号E99
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab32556 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).
ICC 1/250.
Flow Cyt 1/40.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

  • 应用说明Is unsuitable for IHC or IP.
  • 靶标

    • 相关性The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. Two alternatively spliced transcript variants have been described.
    • 细胞定位Cell membrane; Multi-pass membrane protein.
    • 数据库链接
    • 别名
      • C C chemokine receptor D6 antibody
      • C C chemokine receptor type 9 antibody
      • C C CKR 9 antibody
      • CC Chemokine receptor CCR10 antibody
      • CC CKR 9 antibody
      • CCBP2 antibody
      • CCCKR9 antibody
      • CCR 9 antibody
      • CCR9 antibody
      • CDw199 antibody
      • CDw199 antigen antibody
      • Chemokine (C C motif) receptor 9 antibody
      • Chemokine (C C motif) receptor 9, isoform CRA_a antibody
      • Chemokine (C-C motif) receptor 9 isoform A antibody
      • Chemokine (C-C motif) receptor 9 isoform B antibody
      • Chemokine C C motif receptor 9 antibody
      • Chemokine C C receptor 10 antibody
      • Chemokine CC Motif Receptor 9 antibody
      • Chemokine receptor CCR 9 antibody
      • Chemokine receptor CCR9 antibody
      • Chemokine-binding protein D6 antibody
      • Cmkbr10 antibody
      • CMKBR9 antibody
      • G protein coupled receptor 28 antibody
      • GPR 28 antibody
      • GPR 9 6 antibody
      • GPR28 antibody
      • GPR96 antibody
      • OTTHUMP00000164653 antibody
      • OTTHUMP00000164654 antibody
      see all

    Anti-CCR9 antibody [E99] 图像

    Anti-CCR9 antibody [E99] (ab32556)参考文献

    This product has been referenced in:
    • Maeda S  et al. Molecular cloning and expression analysis of the canine chemokine receptor CCR9. Vet Immunol Immunopathol 145:534-9 (2012). WB . Read more (PubMed: 22209203) »
    • Shen X  et al. CC Chemokine Receptor 9 Enhances Proliferation in Pancreatic Intraepithelial Neoplasia and Pancreatic Cancer Cells. J Gastrointest Surg : (2009). WB, Flow Cyt ; Human, Mouse . Read more (PubMed: 19756884) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab32556.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"