生物素Anti-CCR7抗体[4B12] (ab93519)
Key features and details
- Biotin Rat monoclonal [4B12] to CCR7
- Suitable for: Flow Cyt, ICC/IF
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG2a
Related conjugates and formulations
概述
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产品名称
生物素Anti-CCR7抗体[4B12]
参阅全部 CCR7 一抗 -
描述
生物素大鼠单克隆抗体[4B12] to CCR7 -
宿主
Rat -
偶联物
Biotin -
经测试应用
适用于: Flow Cyt, ICC/IFmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse CCR7. Rat basophilic leukaemia (RBL)-2H3 cells transfectanted with Mouse CCR7.
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阳性对照
- Splenocytes or thymocytes.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
4B12 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab93519于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Flow Cyt |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
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说明 |
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Flow Cyt
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
靶标
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功能
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. -
组织特异性
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 12775 Mouse
- SwissProt: P47774 Mouse
- Unigene: 2932 Mouse
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别名
- BLR 2 antibody
- BLR2 antibody
- C C chemokine receptor type 7 antibody
see all
数据表及文件
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Datasheet download
文献 (3)
ab93519 被引用在 3 文献中.
- Waldner H et al. The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells. J Immunol 176:5455-62 (2006). PubMed: 16622013
- Ohl L et al. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 21:279-88 (2004). PubMed: 15308107
- Ritter U et al. Analysis of the CCR7 expression on murine bone marrow-derived and spleen dendritic cells. J Leukoc Biol 76:472-6 (2004). PubMed: 15197229