概述

  • 产品名称Anti-CCR6抗体
    参阅全部 CCR6 一抗
  • 描述
    山羊多克隆抗体to CCR6
  • 经测试应用适用于: IHC-Fr, ELISA, ICC, IHC-Pmore details
  • 种属反应性
    与反应: Human
    不与反应: Mouse
  • 免疫原

    Synthetic peptide:

    YFVSVNTSYYSVDSEMLLCSLQEVRQFSR

    , corresponding to amino acids 18-46 of Human CCR6.

  • 阳性对照
    • Human spleen or peripheral blood

性能

应用

Our Abpromise guarantee covers the use of ab1659 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/250. PubMed: 19095953
ELISA 1/75000.
ICC 1/300.
IHC-P 1/250.

靶标

  • 功能Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.
  • 组织特异性Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BN 1 antibody
    • BN1 antibody
    • C C chemokine receptor type 6 antibody
    • C C CKR 6 antibody
    • C-C chemokine receptor type 6 antibody
    • C-C CKR-6 antibody
    • CC chemokine receptor type 6 antibody
    • CC CKR 6 antibody
    • CC R6 antibody
    • CC-CKR-6 antibody
    • CCCKR6 antibody
    • CCR 6 antibody
    • CCR-6 antibody
    • Ccr6 antibody
    • CCR6_HUMAN antibody
    • CD 196 antibody
    • CD196 antibody
    • CD196 antigen antibody
    • Chemokine (C C motif) receptor 6 antibody
    • Chemokine (C C) receptor 6 antibody
    • Chemokine (CC motif) receptor 6 antibody
    • Chemokine (CC) receptor 6 antibody
    • Chemokine receptor 6 antibody
    • Chemokine receptor like 3 antibody
    • Chemokine receptor-like 3 antibody
    • CKR 6 antibody
    • CKR L3 antibody
    • CKR-L3 antibody
    • CKR6 antibody
    • CKRL3 antibody
    • CMKBR 6 antibody
    • CMKBR6 antibody
    • DCR 2 antibody
    • DCR2 antibody
    • DRY 6 antibody
    • DRY6 antibody
    • G protein coupled receptor 29 antibody
    • G-protein coupled receptor 29 antibody
    • GPR 29 antibody
    • GPR CY4 antibody
    • GPR-CY4 antibody
    • GPR29 antibody
    • GPRCY 4 antibody
    • GPRCY4 antibody
    • LARC receptor antibody
    • Seven transmembrane receptor lymphocyte 22 antibody
    • STRL 22 antibody
    • STRL22 antibody
    see all

Anti-CCR6 antibody 图像

  • Immunohistochemistry on paraffin section of human spleen, at 1/250 dilution.

Anti-CCR6 antibody (ab1659)参考文献

This product has been referenced in:
  • Salim SY  et al. CD83+CCR7- dendritic cells accumulate in the subepithelial dome and internalize translocated Escherichia coli HB101 in the Peyer's patches of ileal Crohn's disease. Am J Pathol 174:82-90 (2009). IHC-Fr ; Human . Read more (PubMed: 19095953) »

See 1 Publication for this product

Product Wall

I was informed that the best negative control is affinity purified goat IgG antibody to a protein that is not expressed on the target cells cells/tissues to be examined. For example affinity purified Goat IgG antibody to Trail-2 or Trail-3 receptor ant...

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Thank you for your enquiry. The molecular weight of this antibody is 425kDa. Please contact us again if you require further information.

The source of ab1659 has replied to me the following: "We agree with the customer that antibody to human CCR6 should not react with the mouse CCR6 because of the significant sequence differences. However, work with mouse white bloods cells showed c...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"