概述
- 产品名称Anti-CCR3抗体
参阅全部 CCR3 一抗 - 描述兔多克隆抗体to CCR3
- 经测试应用适用于: WBmore details
- 种属反应性与反应: Human
预测可用于: Chimpanzee, Gorilla, Orangutan
- 免疫原
Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human CCR3.
- 阳性对照
- This antibody gave a positive signal in both Human Spleen and Thymus tissue lysates.
性能
- 形式Liquid
- 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
- 存储溶液pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading... - 纯度Immunogen affinity purified
- 克隆多克隆
- 同种型IgG
- 研究领域
相关产品
- Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab112515 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Detects a band of approximately 44 kDa (predicted molecular weight: 41 kDa). |
靶标
- 功能Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
- 组织特异性In eosinophils as well as trace amounts in neutrophils and monocytes.
- 序列相似性Belongs to the G-protein coupled receptor 1 family.
- 细胞定位Cell membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 1232 Human
- Omim: 601268 Human
- SwissProt: P51677 Human
- Unigene: 506190 Human
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别名
- B chemokine receptor antibody
- b-chemokine receptor antibody
- C C chemokine receptor type 3 antibody
see all
Anti-CCR3 antibody 图像
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Western blot - Anti-CCR3 antibody (ab112515)All lanes : Anti-CCR3 antibody (ab112515) at 1 µg/ml
Lane 1 : Human spleen tissue lysate - total protein (ab29699)
Lane 2 : Human thymus tissue lysate - total protein (ab30146)
Lysates/proteins at 10 µg per lane.
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique
Performed under reducing conditions.
Predicted band size : 41 kDa
Observed band size : 44 kDa (why is the actual band size different from the predicted?)
Additional bands at : 105 kDa,22 kDa,72 kDa. We are unsure as to the identity of these extra bands.
Exposure time : 16 minutes
Anti-CCR3 antibody (ab112515)参考文献
ab112515 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"