概述

  • 产品名称
  • 描述
    兔多克隆抗体to CCR1
  • 特异性
    ab19013 recognises CCR1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant full length protein (Human): CCR1

  • 阳性对照
    • A357 cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: 50% Glycerol, 1% BSA, PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab19013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 4 µg/ml. Predicted molecular weight: 43 kDa.Can be blocked with CCR1 peptide (ab185720).

靶标

  • 功能
    Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
  • 组织特异性
    Widely expressed in different hematopoietic cells.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C C chemokine receptor type 1 antibody
    • C C CKR 1 antibody
    • C-C chemokine receptor type 1 antibody
    • C-C CKR-1 antibody
    • CC CKR 1 antibody
    • CC-CKR-1 antibody
    • CCR 1 antibody
    • CCR-1 antibody
    • CCR1 antibody
    • CCR1_HUMAN antibody
    • CD 191 antibody
    • CD191 antibody
    • CD191 antigen antibody
    • Chemokine (C C motif) receptor 1 antibody
    • Chemokine C C motif receptor 1 antibody
    • CKR 1 antibody
    • CKR1 antibody
    • CMKBR 1 antibody
    • CMKBR1 antibody
    • CMKR 1 antibody
    • CMKR1 antibody
    • HM145 antibody
    • LD78 receptor antibody
    • Macrophage inflammatory protein 1 alpha /Rantes receptor antibody
    • Macrophage inflammatory protein 1 alpha receptor antibody
    • Macrophage inflammatory protein 1-alpha receptor antibody
    • Mip 1a R antibody
    • MIP 1alpha R antibody
    • MIP-1alpha-R antibody
    • MIP1aR antibody
    • RANTES R antibody
    • RANTES receptor antibody
    • RANTES-R antibody
    • SCYAR1 antibody
    see all

图片

  • Anti-CCR1 antibody (ab19013) at 1 µg/ml + A357 cell lysate

    Predicted band size : 43 kDa
    Observed band size : 43 kDa

实验方案

文献

This product has been referenced in:
  • Hyldahl RD  et al. Satellite cell activity is differentially affected by contraction mode in human muscle following a work-matched bout of exercise. Front Physiol 5:485 (2014). IHC . Read more (PubMed: 25566087) »
  • Barron DA  et al. TGF-ß1 Induces an Age-Dependent Inflammation of Nerve Ganglia and Fibroplasia in the Prostate Gland Stroma of a Novel Transgenic Mouse. PLoS One 5:e13751 (2010). IHC . Read more (PubMed: 21060787) »

See all 2 Publications for this product

客户评价及客户问答

Thank you for contacting us. Since the antibody was raised against the full length protein (Recombinant full length protein (Human): CCR1), and epitope mapping has not been performed - we do not have information about where the antibody binding site w...

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Thank you for contacting us for technical support and the protocol details, the image is very useful to understand the customer's problem. Is the customer using A357 cell lysate, not A375? This is a good positive control and ab19013 should work ver...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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