Anti-CCR1抗体(ab13240)
Key features and details
- Goat polyclonal to CCR1
- Suitable for: ELISA, ICC, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CCR1抗体
参阅全部 CCR1 一抗 -
描述
山羊多克隆抗体to CCR1 -
宿主
Goat -
特异性
Peptide sequence is < 50 % identical to other chemokine receptors in this region. -
经测试应用
适用于: ELISA, ICC, WBmore details -
种属反应性
与反应: Human
预测可用于: Macaque monkey不与反应: Mouse -
免疫原
Synthetic peptide corresponding to Human CCR1 aa 7-24 (N terminal).
Sequence:TEDYDTTTEFDYGDATPC
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阳性对照
- Immunocytochemistry on human peripheral blood leukocytes.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.1% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab13240于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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ICC |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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说明 |
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ELISA
Use at an assay dependent concentration. |
ICC
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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功能
Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. -
组织特异性
Widely expressed in different hematopoietic cells. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1230 Human
- Entrez Gene: 574188 Macaque monkey
- Omim: 601159 Human
- SwissProt: P32246 Human
- Unigene: 301921 Human
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别名
- C C chemokine receptor type 1 antibody
- C C CKR 1 antibody
- C-C chemokine receptor type 1 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab13240 被引用在 1 文献中.
- Sheng H et al. Knockdown of FOXP1 promotes the development of lung adenocarcinoma. Cancer Biol Ther 20:537-545 (2019). PubMed: 30409062