概述

  • 产品名称
  • 描述
    兔多克隆抗体to CCR1
  • 特异性
    ab117416 does not cross reacts with other members of the CCR family.
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human, Monkey
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptides, corresponding to regions within N terminal amino acids 1-50 of Human CCR1 conjugated to carrier protein (AAH64991).

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium azide
    Constituents: Whole serum, Proprietary component
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab117416 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Predicted molecular weight: 41 kDa.
ELISA 1/10000.

靶标

  • 功能
    Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
  • 组织特异性
    Widely expressed in different hematopoietic cells.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C C chemokine receptor type 1 antibody
    • C C CKR 1 antibody
    • C-C chemokine receptor type 1 antibody
    • C-C CKR-1 antibody
    • CC CKR 1 antibody
    • CC-CKR-1 antibody
    • CCR 1 antibody
    • CCR-1 antibody
    • CCR1 antibody
    • CCR1_HUMAN antibody
    • CD 191 antibody
    • CD191 antibody
    • CD191 antigen antibody
    • Chemokine (C C motif) receptor 1 antibody
    • Chemokine C C motif receptor 1 antibody
    • CKR 1 antibody
    • CKR1 antibody
    • CMKBR 1 antibody
    • CMKBR1 antibody
    • CMKR 1 antibody
    • CMKR1 antibody
    • HM145 antibody
    • LD78 receptor antibody
    • Macrophage inflammatory protein 1 alpha /Rantes receptor antibody
    • Macrophage inflammatory protein 1 alpha receptor antibody
    • Macrophage inflammatory protein 1-alpha receptor antibody
    • Mip 1a R antibody
    • MIP 1alpha R antibody
    • MIP-1alpha-R antibody
    • MIP1aR antibody
    • RANTES R antibody
    • RANTES receptor antibody
    • RANTES-R antibody
    • SCYAR1 antibody
    see all

实验方案

Anti-CCR1 antibody (ab117416)参考文献

This product has been referenced in:
  • Tomas-Sanchez C  et al. Prophylactic Chronic Zinc Administration Increases Neuroinflammation in a Hypoxia-Ischemia Model. J Immunol Res 2016:4039837 (2016). WB ; Rat . Read more (PubMed: 27635404) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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