概述

  • 产品名称Anti-CCNDBP1抗体
    参阅全部 CCNDBP1 一抗
  • 描述
    小鼠单克隆抗体to CCNDBP1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Orangutan
  • 免疫原

    Recombinant fragment: LVAENGKKDQ VAQMADIVDI SDEISPSVDD LALSIYPPMC HLTVRINSAK LVSVLKKALE ITKASHVTPQ PEDSWIPLLI NAIDHCMNRI KELTQSELEL , corresponding to amino acids 261-360 of human CCNDBP1 (NP_036274) with a 26 kDa tag

  • 阳性对照
    • CCNDBP1 transfected 293T cell lysate; recombinant tagged fragment of human CCNDBP1 (the immunogen).

性能

应用

Our Abpromise guarantee covers the use of ab77113 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 40 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
  • 组织特异性Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
  • 序列相似性Belongs to the CCNDBP1 family.
  • 发展阶段Expression may increase during differentiation.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AU022347 antibody
    • CCDB1_HUMAN antibody
    • CCNDBP 1 antibody
    • Ccndbp1 antibody
    • Cyclin D type binding protein 1 antibody
    • Cyclin-D1-binding protein 1 antibody
    • D type cyclin interacting protein 1 antibody
    • DIP 1 antibody
    • DIP1 antibody
    • GCIP antibody
    • Grap 2 and cyclin D interacting protein antibody
    • Grap 2 cyclin D interacting protein GCIP antibody
    • Grap 2 cyclin interacting protein antibody
    • Grap2 and cyclin D interacting protein antibody
    • Grap2 and cyclin-D-interacting protein antibody
    • Grap2 cyclin D interacting protein GCIP antibody
    • Grap2 cyclin interacting protein antibody
    • HHM antibody
    • HHM protein antibody
    • Human homolog of Maid antibody
    • MAID antibody
    • MAID protein antibody
    • Maternal inhibition of differentiation antibody
    • MGC109078 antibody
    • OTTMUSP00000017037 antibody
    • RP23 263D22.2 antibody
    • SECC 8 antibody
    • SSEC 8 antibody
    • Stage specific embryonic cDNA 8 antibody
    see all

Anti-CCNDBP1 antibody 图像

  • Anti-CCNDBP1 antibody (ab77113) at 1/500 dilution + recombinant tagged fragment of human CCNDBP1 (the immunogen) at 0.2 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

    Predicted band size : 40 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-CCNDBP1 antibody (ab77113) at 1/500 dilution

    Lane 1 : CCNDBP1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 40 kDa
    Observed band size : 40 kDa

Anti-CCNDBP1 antibody (ab77113)参考文献

ab77113 has not yet been referenced specifically in any publications.

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