概述

  • 产品名称Anti-CCNDBP1抗体
    参阅全部 CCNDBP1 一抗
  • 描述
    山羊多克隆抗体to CCNDBP1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog, Orangutan
  • 免疫原

    Synthetic peptide:

    C-NRIKELTQSELEL

    , corresponding to C terminal amino acids 348-360 of Human CCNDBP1.

  • 阳性对照
    • Human Brain cortex and Human prostate tissues.

性能

应用

Our Abpromise guarantee covers the use of ab110868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
  • 组织特异性Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
  • 序列相似性Belongs to the CCNDBP1 family.
  • 发展阶段Expression may increase during differentiation.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AU022347 antibody
    • CCDB1_HUMAN antibody
    • CCNDBP 1 antibody
    • Ccndbp1 antibody
    • Cyclin D type binding protein 1 antibody
    • Cyclin-D1-binding protein 1 antibody
    • D type cyclin interacting protein 1 antibody
    • DIP 1 antibody
    • DIP1 antibody
    • GCIP antibody
    • Grap 2 and cyclin D interacting protein antibody
    • Grap 2 cyclin D interacting protein GCIP antibody
    • Grap 2 cyclin interacting protein antibody
    • Grap2 and cyclin D interacting protein antibody
    • Grap2 and cyclin-D-interacting protein antibody
    • Grap2 cyclin D interacting protein GCIP antibody
    • Grap2 cyclin interacting protein antibody
    • HHM antibody
    • HHM protein antibody
    • Human homolog of Maid antibody
    • MAID antibody
    • MAID protein antibody
    • Maternal inhibition of differentiation antibody
    • MGC109078 antibody
    • OTTMUSP00000017037 antibody
    • RP23 263D22.2 antibody
    • SECC 8 antibody
    • SSEC 8 antibody
    • Stage specific embryonic cDNA 8 antibody
    see all

Anti-CCNDBP1 antibody 图像

  • ab110868 at 3.75 µg/ml staining CCNDBP1 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry.
  • ab110868 at 3.75 µg/ml staining CCNDBP1 in Formalin-fixed, Paraffin-embedded Human Prostate tissue by Immunohistochemistry.

Anti-CCNDBP1 antibody (ab110868)参考文献

ab110868 has not yet been referenced specifically in any publications.

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