概述

  • 产品名称Anti-CCL14抗体
    参阅全部 CCL14 一抗
  • 描述
    小鼠单克隆抗体to CCL14
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: TKTESSSRGP YHPSECCFTY TTYKIPRQRI MDYYETNSQC SKPGIVFITK RGHSVCTNPS DKWVQDYIKD MKEN, corresponding to amino acids 20-93 of Human CCL14

性能

应用

Our Abpromise guarantee covers the use of ab55752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
    • 组织特异性Expressed constitutively in several normal tissues: spleen, liver, skeletal and heart muscle, gut, and bone marrow, present at high concentrations (1-80 nM) in plasma.
    • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
    • 翻译后修饰The N-terminal processed forms HCC-1(3-74), HCC-1(4-74) and HCC-1(9-74) are produced in small amounts by proteolytic cleavage after secretion in blood.
      HCC-1(1-74), but not HCC-1(3-74) and HCC-1(4-74), is partially O-glycosylated; the O-linked glycan consists of one Gal-GalNAc disaccharide, further modified by two N-acetylneuraminic acids.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CC-1 antibody
      • CC-3 antibody
      • CCL14 antibody
      • CCL14_HUMAN antibody
      • chemokine (C-C motif) ligand 14 antibody
      • Chemokine CC-1/CC-3 antibody
      • chemokine CC1 antibody
      • chemokine CC3 antibody
      • chemokine HCC1 antibody
      • chemokine HCC3 antibody
      • CKb1 antibody
      • HCC-1(1-74) antibody
      • HCC-1(9-74) antibody
      • HCC-1/HCC-3 antibody
      • HCC-3 antibody
      • HCC1 antibody
      • HEMOFILTRATE CC CHEMOKINE 1 antibody
      • MCIF antibody
      • NCC-2 antibody
      • NCC2 antibody
      • new CC chemokine 2 antibody
      • SCYA14 antibody
      • SCYL2 antibody
      • small inducible cytokine subfamily A (Cys-Cys), member 14 antibody
      • Small-inducible cytokine A14 antibody
      • SY14 antibody
      see all

    Anti-CCL14 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab55752 CCL14 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    Anti-CCL14 antibody (ab55752)参考文献

    ab55752 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"