概述

  • 产品名称Anti-CCKAR抗体
    参阅全部 CCKAR 一抗
  • 描述
    兔多克隆抗体to CCKAR
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to the 3rd cytoplasmic domain of Human CCKAR.

  • 阳性对照
    • Human adrenal and prostate tissues.

性能

应用

Our Abpromise guarantee covers the use of ab115287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 10 µg/ml. requires pre-treatment with Proteinase K.

靶标

  • 相关性The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction.
  • 细胞定位Integral membrane protein
  • 数据库链接
  • 别名
    • CCK A antibody
    • CCK A receptor antibody
    • CCK AR antibody
    • CCK-A receptor antibody
    • CCK1 R antibody
    • CCK1-R antibody
    • CCK1R antibody
    • CCKA antibody
    • CCKA receptor antibody
    • CCKR Type A antibody
    • CCKRA antibody
    • Cholecystokinin 1 receptor antibody
    • Cholecystokinin A receptor antibody
    • Cholecystokinin receptor type A antibody
    • Cholecystokinin type A receptor antibody
    see all

Anti-CCKAR antibody 图像

  • ab115287, at 10µg/ml, staining CCKAR in Formalin-fixed, Paraffin-embedded Human Prostate tissue by Immunohistochemistry.
  • ab115287, at 10µg/ml, staining CCKAR in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry.

Anti-CCKAR antibody (ab115287)参考文献

ab115287 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab115287.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"