概述

  • 产品名称Anti-CCK4抗体
    参阅全部 CCK4 一抗
  • 描述
    小鼠单克隆抗体to CCK4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 36-146 of Human CCK4

性能

应用

Our Abpromise guarantee covers the use of ab55633 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
    • 组织特异性Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.
    • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
      Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 protein kinase domain.
    • 结构域The protein kinase domain is predicted to be catalytically inactive.
    • 翻译后修饰MMP14 cleaves PTK7 between Pro-621 and Leu-622 generating an N-terminal soluble (70 kDa) fragment and a membrane C-terminal (50 kDa) fragment. Proteolysis by MMP14 regulates PTK7 function in non-canonical Wnt signaling pathway.
    • 细胞定位Membrane. Cell junction. Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 8430404F20Rik antibody
      • CCK 4 antibody
      • CCK-4 antibody
      • Colon carcinoma kinase 4 antibody
      • Human colon carcinoma kinase 4 (CCK4) mRNA complete cds antibody
      • Inactive tyrosine-protein kinase 7 antibody
      • mPTK7/CCK4 antibody
      • OTTHUMP00000217016 antibody
      • Protein tyrosine kinase PTK 7 antibody
      • Protein-tyrosine kinase 7 antibody
      • Pseudo tyrosine kinase receptor 7 antibody
      • PTK 7 antibody
      • PTK7 antibody
      • PTK7 protein tyrosine kinase 7 antibody
      • PTK7 protein tyrosine kinase antibody
      • PTK7_HUMAN antibody
      • Serum response factor antibody
      • Srf antibody
      • Tyrosine-protein kinase-like 7 antibody
      see all

    Anti-CCK4 antibody 图像



    • Predicted band size : 118 kDa
      CCK4 antibody (ab55633) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    Anti-CCK4 antibody (ab55633)参考文献

    ab55633 has not yet been referenced specifically in any publications.

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