概述

  • 产品名称Anti-CCDC88C抗体
  • 描述
    兔多克隆抗体to CCDC88C
  • 经测试应用适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment corresponding to amino acids 1571-1698 of Human CCDC88C.

  • 阳性对照
    • Human testis tissue

性能

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应用

Our Abpromise guarantee covers the use of ab121235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6.0

靶标

  • 功能Negative regulator of the canonical Wnt signaling pathway, acting downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization.
  • 序列相似性Belongs to the CCDC88 family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ccdc88c antibody
    • Coiled-coil domain-containing protein 88C antibody
    • DAPLE antibody
    • DAPLE_HUMAN antibody
    • Dvl-associating protein with a high frequency of leucine residues antibody
    • hDaple antibody
    • HkRP2 antibody
    • Hook-related protein 2 antibody
    • KIAA1509 antibody
    • Protein Daple antibody
    see all

Anti-CCDC88C antibody 图像

  • Immunofluorescent staining of Human cell line A-431 shows positivity in nucleus and nucleoli. Recommended concentration of ab121235 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • Immunohistochemical staining of paraffin embedded Human testis tissue, using 1/350 ab121235, shows strong nuclear positivity in cells of seminiferus ducts and Leydig cells.

Anti-CCDC88C antibody (ab121235)参考文献

ab121235 has not yet been referenced specifically in any publications.

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