概述

  • 产品名称Anti-CCDC6抗体
    参阅全部 CCDC6 一抗
  • 描述
    兔多克隆抗体to CCDC6
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 208-237 of Human CCDC6

  • 阳性对照
    • Hela cell line lysates

性能

应用

Our Abpromise guarantee covers the use of ab103257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 66 kDa.

靶标

  • 组织特异性Ubiquitously expressed.
  • 疾病相关Defects in CCDC6 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving CCDC6 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.
  • 结构域The protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton. May be a cytoskeletal protein.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CCDC 6 antibody
    • CCDC6 antibody
    • CCDC6_HUMAN antibody
    • Coiled coil domain containing 6 antibody
    • Coiled coil domain containing protein 6 antibody
    • Coiled-coil domain-containing protein 6 antibody
    • D10S170 antibody
    • FLJ32286 antibody
    • H4 antibody
    • Papillary thyroid carcinoma encoded protein antibody
    • Papillary thyroid carcinoma-encoded protein antibody
    • Protein H4 antibody
    • PTC antibody
    • TPC antibody
    • TST 1 antibody
    • TST1 antibody
    see all

Anti-CCDC6 antibody 图像

  • Anti-CCDC6 antibody (ab103257) at 1/100 dilution + HeLa cell lysate at 35 µg

    Predicted band size : 66 kDa

Anti-CCDC6 antibody (ab103257)参考文献

ab103257 has not yet been referenced specifically in any publications.

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