概述

  • 产品名称Anti-CCDC50抗体
    参阅全部 CCDC50 一抗
  • 描述
    兔多克隆抗体to CCDC50
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 85-114 of Human CCDC50 (NP_777568.1, NP_848018.1).

  • 阳性对照
    • A549 cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab123320 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 36 kDa.

靶标

  • 功能Involved in EGFR signaling.
  • 组织特异性Isoform 1 and isoform 2 are co-expressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart.
  • 疾病相关Defects in CCDC50 are the cause of deafness autosomal dominant type 44 (DFNA44) [MIM:607453]. A form of non-syndromic hearing loss. It is initially moderate and affects mainly low to mid frequencies. Later, it progresses to involve all the frequencies and leads to a profound hearing loss by the 6th decade. The onset of the hearing loss occurs in the first decade of life.
  • 翻译后修饰Phosphorylated on tyrosine residues.
  • 细胞定位Cytoplasm. Associated with microtubules of the cytoskeleton and mitotic apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C3orf6 antibody
    • C3orf6 YMER antibody
    • CCD50_HUMAN antibody
    • CCDC 50 antibody
    • Ccdc50 antibody
    • Chromosome 3 open reading frame 6 antibody
    • Coiled coil domain containing 50 antibody
    • Coiled coil domain containing protein 50 antibody
    • Coiled-coil domain-containing protein 50 antibody
    • Protein Ymer antibody
    • Ymer antibody
    • Ymer protein antibody
    see all

Anti-CCDC50 antibody 图像

  • Anti-CCDC50 antibody (ab123320) at 1/100 dilution + A549 cell line lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 36 kDa

Anti-CCDC50 antibody (ab123320)参考文献

ab123320 has not yet been referenced specifically in any publications.

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