概述

  • 产品名称Anti-CCBL1抗体
    参阅全部 CCBL1 一抗
  • 描述
    小鼠单克隆抗体to CCBL1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length human CCBL1 protein (AAH33685) with a 26 kDa tag.

  • 阳性对照
    • CCBL1 transfected 293T cell lysate; immunogen

性能

应用

Our Abpromise guarantee covers the use of ab76963 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 48 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 相关性CCBL1 is a cytosolic enzyme which is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism leads to the formation of reactive metabolites which can lead to nephrotoxicity and neurotoxicity. CCBL1 catalyzes the irreversible transamination of the L-tryptophan metabolite L-kinurenine to form kynurenic acid (KA). It catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. This enzyme has a central role in the bioactivation of nephrotoxic halogenated hydrocarbons - the possibility of human exposure to these chemicals has focused interest on the CCBL1 from human kidney.
  • 细胞定位Cytoplasmic
  • 数据库链接
  • 别名
    • Beta lyase antibody
    • Beta lysase, kidney antibody
    • CCBL 1 antibody
    • Cysteine conjugate beta lyase antibody
    • Cysteine conjugate beta lyase, cytoplasmic antibody
    • Cysteine conjugate beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) antibody
    • Cysteine S conjugate beta lyase antibody
    • Cytoplasmic cysteine conjugate beta lyase antibody
    • FLJ95217 antibody
    • Glutamine phenylpyruvate aminotransferase antibody
    • Glutamine transaminase K antibody
    • GTK antibody
    • KAT1 antibody
    • KATI antibody
    • Kyneurenine aminotransferase antibody
    • Kynurenine aminotransferase I antibody
    • Kynurenine oxoglutarate transaminase 1 antibody
    • MGC29624 antibody
    • OTTHUMP00000022311 antibody
    • OTTHUMP00000022312 antibody
    see all

Anti-CCBL1 antibody 图像

  • Anti-CCBL1 antibody (ab76963) at 5 µg/ml + immunogen at 0.2 µg

    Secondary
    Goat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

    Predicted band size : 48 kDa
    Observed band size : 68 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-CCBL1 antibody (ab76963) at 5 µg/ml

    Lane 1 : CCBL1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

    Predicted band size : 48 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)

Anti-CCBL1 antibody (ab76963)参考文献

ab76963 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab76963.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"