概述

  • 产品名称Anti-CCBE1抗体
    参阅全部 CCBE1 一抗
  • 描述
    兔多克隆抗体to CCBE1
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>95%) recombinant Human CCBE1 (amino acids 35-406) derived from Sf9 insect cells.

  • 阳性对照
    • Human foreskin tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液pH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明Endotoxin level: < 0.1 EU/1µg of the antibody (LAL).
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2 - 5 µg/ml. Predicted molecular weight: 44 kDa.
ICC/IF Use a concentration of 2 - 10 µg/ml.

靶标

  • 功能Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.
  • 组织特异性Not expressed in blood or lymphatic endothelial cells.
  • 疾病相关Defects in CCBE1 are the cause of Hennekam lymphangiectasia-lymphedema syndrome (HLYLMP) [MIM:235510]. HLYLMP is a generalized lymph-vessels dysplasia characterized by intestinal lymphangiectasia with severe lymphedema of the limbs, genitalia and face. In addition, affected individuals have unusual facies and severe mental retardation.
  • 序列相似性Belongs to the CCBE1 family.
    Contains 2 collagen-like domains.
    Contains 1 EGF-like domain.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CCBE 1 antibody
    • ccbe1 antibody
    • CCBE1_HUMAN antibody
    • Collagen and calcium binding EGF domain containing protein 1 antibody
    • Collagen and calcium binding EGF domains 1 antibody
    • Collagen and calcium-binding EGF domain-containing protein 1 antibody
    • FLJ30681 antibody
    • Full of fluid protein homolog antibody
    • MGC50861 antibody
    see all

Anti-CCBE1 antibody 图像

  • Immunofluorescent images showing Human foreskin (left hand image) and negative control of a consecutive section (right hand image), stained with ab111495 at a 1/50 dilution. Epidermial and scattered cells in the dermis are stained green (left hand image), whereas nuclei are counter-stained blue (right hand image: negative control of a consecutive section).

Anti-CCBE1 antibody (ab111495)参考文献

ab111495 has not yet been referenced specifically in any publications.

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