概述

  • 产品名称
  • 描述
    兔多克隆抗体to CCBE1
  • 经测试应用
    适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>95%) recombinant Human CCBE1 (amino acids 35-406) derived from Sf9 insect cells.

  • 阳性对照
    • Human foreskin tissue

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    pH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 纯化说明
    Endotoxin level: < 0.1 EU/1µg of the antibody (LAL).
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2 - 5 µg/ml. Predicted molecular weight: 44 kDa.
ICC/IF Use a concentration of 2 - 10 µg/ml.

靶标

  • 功能
    Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.
  • 组织特异性
    Not expressed in blood or lymphatic endothelial cells.
  • 疾病相关
    Defects in CCBE1 are the cause of Hennekam lymphangiectasia-lymphedema syndrome (HLYLMP) [MIM:235510]. HLYLMP is a generalized lymph-vessels dysplasia characterized by intestinal lymphangiectasia with severe lymphedema of the limbs, genitalia and face. In addition, affected individuals have unusual facies and severe mental retardation.
  • 序列相似性
    Belongs to the CCBE1 family.
    Contains 2 collagen-like domains.
    Contains 1 EGF-like domain.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CCBE 1 antibody
    • ccbe1 antibody
    • CCBE1_HUMAN antibody
    • Collagen and calcium binding EGF domain containing protein 1 antibody
    • Collagen and calcium binding EGF domains 1 antibody
    • Collagen and calcium-binding EGF domain-containing protein 1 antibody
    • FLJ30681 antibody
    • Full of fluid protein homolog antibody
    • MGC50861 antibody
    see all

图片

  • Immunofluorescent images showing Human foreskin (left hand image) and negative control of a consecutive section (right hand image), stained with ab111495 at a 1/50 dilution. Epidermial and scattered cells in the dermis are stained green (left hand image), whereas nuclei are counter-stained blue (right hand image: negative control of a consecutive section).

文献

ab111495 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab111495.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册