概述

  • 产品名称Anti-CCBE1抗体
    参阅全部 CCBE1 一抗
  • 描述
    兔多克隆抗体to CCBE1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human, Zebrafish
    预测可用于: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 287-336 (PMGPSPDLSH IKQGRRGPVG PPGAPGRDGS KGERGAPGPR GSPGPPGSFD) of Human CCBE1 (NP_597716).

  • 阳性对照
    • ACHN cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab101967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.
  • 组织特异性Not expressed in blood or lymphatic endothelial cells.
  • 疾病相关Defects in CCBE1 are the cause of Hennekam lymphangiectasia-lymphedema syndrome (HLYLMP) [MIM:235510]. HLYLMP is a generalized lymph-vessels dysplasia characterized by intestinal lymphangiectasia with severe lymphedema of the limbs, genitalia and face. In addition, affected individuals have unusual facies and severe mental retardation.
  • 序列相似性Belongs to the CCBE1 family.
    Contains 2 collagen-like domains.
    Contains 1 EGF-like domain.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CCBE 1 antibody
    • ccbe1 antibody
    • CCBE1_HUMAN antibody
    • Collagen and calcium binding EGF domain containing protein 1 antibody
    • Collagen and calcium binding EGF domains 1 antibody
    • Collagen and calcium-binding EGF domain-containing protein 1 antibody
    • FLJ30681 antibody
    • Full of fluid protein homolog antibody
    • MGC50861 antibody
    see all

Anti-CCBE1 antibody 图像

  • Anti-CCBE1 antibody (ab101967) at 1 µg/ml + ACHN cell lysate at 10 µg

    Predicted band size : 44 kDa

Anti-CCBE1 antibody (ab101967)参考文献

This product has been referenced in:
  • Le Guen L  et al. Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis. Development 141:1239-49 (2014). WB ; Zebrafish . Read more (PubMed: 24523457) »

See 1 Publication for this product

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