概述

  • 产品名称Anti-CC2D1A抗体
    参阅全部 CC2D1A 一抗
  • 描述
    兔多克隆抗体to CC2D1A
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 1 and 50 of human CC2D1A (NP_060191.3).

  • 阳性对照
    • Anaplastic thyroid carcinoma, breast carcinoma, colon carcinoma, ovarian carcinoma, prostate carcinoma, stomach adenocarcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab87279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Antigen retrieval with tris-EDTA buffer pH 9 recommended.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性CC2D1A belongs to the CC2D1 family. It contains one C2 domain. It is a transcription factor that binds specifically to the FRE (five repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. CC2D1A may play a role in the altered regulation of HTR1A associated with anxiety and major depression. It also mediates HDAC-independent repression of HTR1A promoter in neuronal cell. There are three named isoforms. Defects in CC2D1A are the cause of non-syndromic mental retardation autosomal recessive type 3 (MRT3). Patients display severe mental retardation and psychomotor development delay in early childhood. Non-syndromic mental retardation patients do not manifest other clinical signs.
    • 细胞定位Cytoplasm. Nucleus.
    • 数据库链接
    • 别名
      • Akt kinase interacting protein 1 antibody
      • Coiled coil and C2 domain containing 1A antibody
      • Coiled coil and C2 domain containing protein 1A antibody
      • Five repressor element under dual repression binding protein 1 antibody
      • FLJ20241 antibody
      • FLJ41160 antibody
      • FRE under dual repression binding protein 1 antibody
      • FREUD 1 antibody
      • Freud 1/Aki1 antibody
      • Mental retardation, nonsyndromic, autosomal recessive, 3 antibody
      • MRT3 antibody
      • Putative NF kappa B activating protein 023N antibody
      • Putative NF kappa B activating protein antibody
      see all

    Anti-CC2D1A antibody 图像

    • ab87279, at a 1/250 dilution, staining CC2D1A in formalin fixed, paraffin embedded Human breast carcinoma tissue by Immunohistochemistry.
      Detection: DAB staining.
    • ab87279, at a 1/250 dilution, staining CC2D1A in formalin fixed, paraffin embedded Human thyroid carcinoma tissue by Immunohistochemistry.
      Detection: by DAB staining.
    • ab87279, at a 1/100 dilution, staining CC2D1A in formalin fixed, paraffin embedded Human prostate carcinoma tissue by Immunohistochemistry.

      Detection: Goat anti-Rabbit IgG conjugated with a red-fluorescent dye, at a 1/100 dilution.

    Anti-CC2D1A antibody (ab87279)参考文献

    ab87279 has not yet been referenced specifically in any publications.

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