产品名称 Anti-CBX1 / HP1 beta抗体 参阅全部 CBX1 / HP1 beta 一抗
兔多克隆抗体to CBX1 / HP1 beta
ELISA, WB, IHC-P more details
Synthetic peptide from the N-terminal region of human CBX4, conjugated to KLH
Mouse kidney lysate; Human hepatocarcinoma tissue.
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
存储溶液 Preservative: 0.09% Sodium Azide
Concentration information loading...
纯度 Protein G purified
纯化说明 The antibody was purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 61 kDa.
1/50 - 1/100.
功能 Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
组织特异性 Expressed in all adult and embryonic tissues.
序列相似性 Contains 2 chromo domains.
翻译后修饰 Not phosphorylated. Ubiquitinated.
细胞定位 Nucleus. Unassociated with chromosomes during mitosis.
Information by UniProt
CBX 1 antibody
Anti-CBX1 / HP1 beta antibody 图像
Western blot - CBX1 / HP1 beta antibody (ab71635)
Anti-CBX1 / HP1 beta antibody (ab71635) at 1/100 dilution + Mouse kidney tissue lysate at 12.5 µg Predicted band size : 61 kDa Observed band size : 61 kDa Additional bands at : 25 kDa,36 kDa,45 kDa. We are unsure as to the identity of these extra bands.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CBX1 / HP1 beta antibody (ab71635)
Analysis of CBX4 expression on formalin-fixed and paraffin-embedded human hepatocarcinoma tissue using ab71635 at 1:50 dilution (peroxidase conjugation secondary antibody, AEC staining).
Anti-CBX1 / HP1 beta antibody (ab71635)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"