概述

  • 产品名称
    Anti-CBR1抗体(HRP)
    参阅全部 CBR1 一抗
  • 描述
    山羊多克隆抗体to CBR1 (HRP)
  • 偶联物
    HRP
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-HGQFVSEKRVEQW

    , corresponding to C terminal amino acids 265-277 of Human CBR1 according to NP_001748.1.

  • 阳性对照
    • Human liver lysates.
  • 常规说明

    Conjugated via amine groups to horseradish peroxidise.

性能

应用

Our Abpromise guarantee covers the use of ab124170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 30 kDa.

靶标

  • 功能
    NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
  • 序列相似性
    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 15 hydroxyprostaglandin dehydrogenase [NADP+] antibody
    • 15-hydroxyprostaglandin dehydrogenase [NADP+] antibody
    • Carbonyl reductase [NADPH] 1 antibody
    • Carbonyl Reductase 1 antibody
    • CBR 1 antibody
    • CBR1 antibody
    • CBR1_HUMAN antibody
    • CRN antibody
    • NADPH dependent carbonyl reductase 1 antibody
    • NADPH-dependent carbonyl reductase 1 antibody
    • Prostaglandin 9 ketoreductase antibody
    • Prostaglandin 9-ketoreductase antibody
    • Prostaglandin E(2) 9 reductase antibody
    • Prostaglandin-E(2) 9-reductase antibody
    • SDR21C1 antibody
    see all

图片

  • Anti-CBR1 antibody (HRP) (ab124170) at 1/1000 dilution + Human liver lysates in RIPA buffer at 35 µg

    Predicted band size : 30 kDa

实验方案

文献

ab124170 has not yet been referenced specifically in any publications.

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