Anti-Cathepsin E抗体(ab89414)

概述

  • 产品名称
    Anti-Cathepsin E抗体
    参阅全部 Cathepsin E 一抗
  • 描述
    小鼠多克隆抗体to Cathepsin E
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 18 - 397 of Human Cathepsin E

  • 阳性对照
    • Stomach lysate

性能

应用

Our Abpromise guarantee covers the use of ab89414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.

靶标

  • 功能
    May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
  • 组织特异性
    Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes.
  • 序列相似性
    Belongs to the peptidase A1 family.
  • 翻译后修饰
    Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide.
    Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57.
  • 细胞定位
    Endosome. The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CATE antibody
    • CATE_HUMAN antibody
    • Cathepsin E antibody
    • Cathepsin E form II antibody
    • CTSE antibody
    • Erythrocyte membrane aspartic proteinase antibody
    • Slow moving proteinase antibody
    see all

图片

  • Anti-Cathepsin E antibody (ab89414) at 1 µg/ml + Human stomach lysate at 50 µg

    Predicted band size : 43 kDa
  • All lanes : Anti-Cathepsin E antibody (ab89414) at 1 µg/ml

    Lane 1 : Cathepsin E transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 43 kDa
    Observed band size : 43 kDa

实验方案

文献

ab89414 has not yet been referenced specifically in any publications.

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