Anti-Cathepsin E抗体(ab89414)
Key features and details
- Mouse polyclonal to Cathepsin E
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Cathepsin E抗体
参阅全部 Cathepsin E 一抗 -
描述
小鼠多克隆抗体to Cathepsin E -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment, corresponding to amino acids 18 - 397 of Human Cathepsin E
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阳性对照
- Stomach lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab89414于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.
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说明 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa. |
靶标
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功能
May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. -
组织特异性
Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes. -
序列相似性
Belongs to the peptidase A1 family. -
翻译后修饰
Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide.
Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57. -
细胞定位
Endosome. The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. - Information by UniProt
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数据库链接
- Entrez Gene: 1510 Human
- Omim: 116890 Human
- SwissProt: P14091 Human
- Unigene: 644082 Human
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别名
- CATE antibody
- CATE_HUMAN antibody
- Cathepsin E antibody
see all
图片
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Anti-Cathepsin E antibody (ab89414) at 1 µg/ml + Human stomach lysate at 50 µg
Predicted band size: 43 kDa -
All lanes : Anti-Cathepsin E antibody (ab89414) at 1 µg/ml
Lane 1 : Cathepsin E transfected 293T cell lysate
Lane 2 : Non-transfected lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 43 kDa
Observed band size: 43 kDa
数据表及文件
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Datasheet download
文献 (0)
ab89414 尚未被引用在任何文献中。