产品名称 Anti-Cathepsin B抗体 参阅全部 Cathepsin B 一抗
兔多克隆抗体to Cathepsin B
特异性 ab30443 recognises liver Cathepsin B. Does not crossreact with Cathepsin L or Cathepsin H.
ELISA, WB, ICC/IF, IP more details
Full length native protein (purified): Cathepsin B from Human liver.
存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
Concentration information loading...
纯度 IgG fraction
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250 - 1/500.
1/1000 - 1/5000. Predicted molecular weight: 38 kDa.
Use at an assay dependent concentration. See Abreview.
Use at an assay dependent concentration. PubMed: 24833013
功能 Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
序列相似性 Belongs to the peptidase C1 family.
细胞定位 Lysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Information by UniProt
Amyloid precursor protein secretase antibody
APP secretase antibody
Anti-Cathepsin B antibody (ab30443)参考文献
This product has been referenced in:
et al. Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms. Exp Mol Med 46:e95 (2014).
Read more (PubMed: 24833013) »
et al. Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action. Exp Eye Res 90:261-6 (2010).
Read more (PubMed: 19895809) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"