Anti-Cathelicidin抗体[mAbcam 58387] (ab58387)

概述

  • 产品名称
    Anti-Cathelicidin抗体[mAbcam 58387]
    参阅全部 Cathelicidin 一抗
  • 描述
    小鼠单克隆抗体[mAbcam 58387] to Cathelicidin
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human Cathelicidin.

  • 阳性对照
    • This antibody gave a positive signal in human spleen tissue lysate.
  • 常规说明

    This antibody clone is manufactured by Abcam.


    CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    IgG fraction
  • Primary antibody说明
    CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein.
  • 克隆
    单克隆
  • 克隆编号
    mAbcam 58387
  • 骨髓瘤
    Sp2/0-Ag14
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab58387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 10 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).

靶标

  • 功能
    Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
  • 组织特异性
    Expressed in bone marrow and testis and neutrophils.
  • 序列相似性
    Belongs to the cathelicidin family.
  • 翻译后修饰
    The N-terminus is blocked.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 18 kDa cationic antimicrobial protein antibody
    • Antibacterial peptide LL-37 antibody
    • Antibacterial protein FALL-39 antibody
    • CAMP antibody
    • CAMP_HUMAN antibody
    • CAP 18 antibody
    • CAP-18 antibody
    • CAP18 antibody
    • Cathelicidin antimicrobial peptide antibody
    • Cathelin-like protein antibody
    • Cathelin-related antimicrobial peptide antibody
    • CATHL3 antibody
    • Cationic antimicrobial protein, 18-KD antibody
    • CLP antibody
    • Cnlp antibody
    • Cramp antibody
    • CRAMP, mouse, homolog of antibody
    • FALL 39 antibody
    • FALL-39 peptide antibiotic antibody
    • FALL39 antibody
    • hCAP 18 antibody
    • hCAP-18 antibody
    • hCAP18 antibody
    • HSD26 antibody
    • LL37 antibody
    • MCLP antibody
    • Peptide antibiotic, PR-39, porcine, homolog of antibody
    see all

图片

  • Anti-Cathelicidin antibody [mAbcam 58387] (ab58387) at 10 µg/ml + Human spleen tissue lysate - total protein (ab29699) at 20 µg

    Secondary
    Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 19 kDa
    Observed band size : 19 kDa
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 30 seconds

实验方案

文献

ab58387 has not yet been referenced specifically in any publications.

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