概述

  • 产品名称
  • 描述
    兔多克隆抗体to CASS4
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 609-639 of Human CASS4 isoform 1 (NP_065089.2, NP_001157588.1) and isoform 2 (NP_001157586.1).

  • 阳性对照
    • MDA-MB435 cell line lysatesm

性能

应用

Our Abpromise guarantee covers the use of ab116022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 87 kDa.

靶标

  • 功能
    Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.
  • 组织特异性
    Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.
  • 序列相似性
    Belongs to the CAS family.
    Contains 1 SH3 domain.
  • 翻译后修饰
    Phosphorylated on tyrosines by SRC.
  • 细胞定位
    Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C20orf32 antibody
    • Cas scaffolding protein family member 4 antibody
    • CAS4 antibody
    • CASS4 antibody
    • CASS4_HUMAN antibody
    • HEF-like protein antibody
    • HEF1-EFS-p130Cas-like protein antibody
    • HEFL antibody
    • HEPL antibody
    • OTTHUMP00000031328 antibody
    • OTTHUMP00000031329 antibody
    see all

图片

  • Anti-CASS4 antibody (ab116022) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

    Predicted band size : 87 kDa

实验方案

文献

ab116022 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab116022.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册