概述

  • 产品名称Anti-CASS4抗体
    参阅全部 CASS4 一抗
  • 描述
    兔多克隆抗体to CASS4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 609-639 of Human CASS4 isoform 1 (NP_065089.2, NP_001157588.1) and isoform 2 (NP_001157586.1).

  • 阳性对照
    • MDA-MB435 cell line lysatesm

性能

应用

Our Abpromise guarantee covers the use of ab116022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 87 kDa.

靶标

  • 功能Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.
  • 组织特异性Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.
  • 序列相似性Belongs to the CAS family.
    Contains 1 SH3 domain.
  • 翻译后修饰Phosphorylated on tyrosines by SRC.
  • 细胞定位Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C20orf32 antibody
    • Cas scaffolding protein family member 4 antibody
    • CAS4 antibody
    • CASS4 antibody
    • CASS4_HUMAN antibody
    • HEF-like protein antibody
    • HEF1-EFS-p130Cas-like protein antibody
    • HEFL antibody
    • HEPL antibody
    • OTTHUMP00000031328 antibody
    • OTTHUMP00000031329 antibody
    see all

Anti-CASS4 antibody 图像

  • Anti-CASS4 antibody (ab116022) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

    Predicted band size : 87 kDa

Anti-CASS4 antibody (ab116022)参考文献

ab116022 has not yet been referenced specifically in any publications.

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