Caspase 6 Inhibitor Drug Detection试剂盒(ab102494)

概述

  • 产品名称
    Caspase 6 Inhibitor Drug Detection试剂盒
    参阅全部 Caspase 6 试剂盒
  • 样品类型
    Adherent cells, Suspension cells
  • 检测类型
    Quantitative
  • 检测时间
    1h 30m
  • 产品概述

    Abcam's Caspase 6 Inhibitor Drug Detection Kit provides an effective means for screening caspase inhibitors using fluorometric methods. The assay utilizes synthetic peptide substrate VEID-AFC (AFC, 7-amino-4-trifluoromethyl coumarin). Active caspase 6 cleaves the synthetic substrate to release free AFC which can then be quantified by fluorometry. Compounds to be screened can directly be added to the reaction and the level of inhibition of caspase 6 activity can be determined by comparison of the fluorescence intensity in samples with and without the testing inhibitors.
    Visit our FAQs page for tips and troubleshooting.

  • 说明

    Caspases have been shown to play a crucial role in apoptosis induced by various deleterious and physiologic stimuli. Inhibition of caspases can delay apoptosis, implicating a potential role in drug screening efforts.

  • 经测试应用
    适用于: Functional Studiesmore details

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab102494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Functional Studies Use at an assay dependent dilution.

实验方案

文献

ab102494 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your inquiry. This kit is generally used with cell lysates, but theoretically it could be used for blood and other samples. This kit is intended for research use only because it is not validated for patient clinical samples. It is ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册