Anti-Caspase-6抗体[M378] (ab119760)

概述

  • 产品名称Anti-Caspase-6抗体[M378]
    参阅全部 Caspase-6 一抗
  • 描述
    小鼠单克隆抗体[M378] to Caspase-6
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human Caspase-6 (C terminal).
    Database link: P55212

  • 阳性对照
    • Human Jurkat, K562 and A431 cell lysates.
  • 常规说明

    Do not aliquot.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab119760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/250. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).

靶标

  • 功能Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • 序列相似性Belongs to the peptidase C14A family.
  • 翻译后修饰Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

Anti-Caspase-6 antibody [M378] 图像

  • Lane 1 : Anti-Caspase 3 at 1/500 dilution
    Lane 2 : Anti-Caspase 3 at 1/1000 dilution
    Lane 3 : Anti-Caspase-6 antibody [M378] (ab119760) at 1/250 dilution
    Lane 4 : Anti-Caspase-6 antibody [M378] (ab119760) at 1/500 dilution
    Lane 5 : Anti-Caspase 7 at 1/500 dilution
    Lane 6 : Anti-Caspase 7 at 1/1000 dilution
    Lane 7 : Anti-Caspase 8 at 1/250 dilution
    Lane 8 : Anti-Caspase 8 at 1/500 dilution

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate
    Lane 3 : Jurkat cell lysate
    Lane 4 : Jurkat cell lysate
    Lane 5 : Jurkat cell lysate
    Lane 6 : Jurkat cell lysate
    Lane 7 : Jurkat cell lysate
    Lane 8 : Jurkat cell lysate


    Predicted band size : 33 kDa

Anti-Caspase-6 antibody [M378] (ab119760)参考文献

ab119760 has not yet been referenced specifically in any publications.

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