Anti-Caspase-6抗体(ab2552)

概述

  • 产品名称Anti-Caspase-6抗体
    参阅全部 Caspase-6 一抗
  • 描述
    兔多克隆抗体to Caspase-6
  • 特异性This antibody recognizes a full length (35 kDa) and the cleaved fragment (15 kDa) of Caspase-6. The antibody specificity is confirmed by peptide inhibition studies.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Rat Caspase-6 (C terminal).
    Database link: P55212
    (Peptide available as ab38263)

性能

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应用

Our Abpromise guarantee covers the use of ab2552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Can be blocked with Caspase-6 peptide (ab38263).

靶标

  • 功能Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • 序列相似性Belongs to the peptidase C14A family.
  • 翻译后修饰Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

Anti-Caspase-6 antibody 图像

  • Western Blot analysis of rat kidney tissue lysate labeling Caspase-6 with ab2552. Both full length and the cleaved large fragment have been detected.

Anti-Caspase-6 antibody (ab2552)参考文献

ab2552 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I can confirm that ab52295 and ab2552 are both rabbit polyclonals. They have also both been purified by affinity purification. So they are quite similar. However, I can confirm they are sourced from different places,...

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