产品名称 Anti-Caspase-6抗体 参阅全部 Caspase-6 一抗
特异性 Detects endogenous levels of the large subunit of Caspase-6 resulting from cleavage at Asp162. This antibody does not recognize other cleaved caspases.
ELISA, WB more details
Mouse, Rat, Human
Synthetic peptide corresponding to Rat Caspase-6 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). Synthetic peptide derived from the carboxy-terminal sequence of p18, the large subunit of rat caspase-6
Database link: P55212
存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: None
Constituents: 50% Glycerol, 0.1mg/ml BSA, 150mM Sodium chloride, 10mM HEPES. pH 7.5
Concentration information loading...
纯度 Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution.
1/1000. Predicted molecular weight: 20 kDa.
功能 Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
序列相似性 Belongs to the peptidase C14A family.
翻译后修饰 Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
Information by UniProt
Apoptotic protease Mch-2 antibody
Apoptotic protease MCH2 antibody
Anti-Caspase-6 antibody (ab18520)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"