概述

  • 产品名称Anti-Caspase-6抗体
    参阅全部 Caspase-6 一抗
  • 描述
    兔多克隆抗体to Caspase-6
  • 特异性Detects endogenous levels of the large subunit of Caspase-6 resulting from cleavage at Asp162. This antibody does not recognize other cleaved caspases.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Rat Caspase-6 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). Synthetic peptide derived from the carboxy-terminal sequence of p18, the large subunit of rat caspase-6
    Database link: P55212

性能

应用

Our Abpromise guarantee covers the use of ab18520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
WB 1/1000. Predicted molecular weight: 20 kDa.

靶标

  • 功能Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • 序列相似性Belongs to the peptidase C14A family.
  • 翻译后修饰Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

Anti-Caspase-6 antibody (ab18520)参考文献

ab18520 has not yet been referenced specifically in any publications.

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