概述

  • 产品名称Anti-Caspase-6抗体
    参阅全部 Caspase-6 一抗
  • 描述
    兔多克隆抗体to Caspase-6
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Full length protein corresponding to Human Caspase-6 aa 1-293.
    Database link: P55212

  • 阳性对照
    • Mouse lung tissue lysate, Caspase-6 transfected 293T cell line lysate, HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab103570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 33 kDa.
ICC/IF 1/200.

靶标

  • 功能Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • 序列相似性Belongs to the peptidase C14A family.
  • 翻译后修饰Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

Anti-Caspase-6 antibody 图像

  • Anti-Caspase-6 antibody (ab103570) at 1/500 dilution + Mouse lung tissue lysate at 25 µg

    Predicted band size : 33 kDa
  • All lanes : Anti-Caspase-6 antibody (ab103570) at 1/500 dilution

    Lane 1 : Caspase 6 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 33 kDa
  • Proximity Ligation Analysis (PLA) of protein-protein interactions between CASP6 and APP.
    ab103570 at 1:200 dilution staining HeLa cells with anti-APP mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex.

Anti-Caspase-6 antibody (ab103570)参考文献

ab103570 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab103570.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"